H
Hongbo Wang
Researcher at Yantai University
Publications - 131
Citations - 2745
Hongbo Wang is an academic researcher from Yantai University. The author has contributed to research in topics: In vivo & Paclitaxel. The author has an hindex of 25, co-authored 126 publications receiving 1808 citations. Previous affiliations of Hongbo Wang include Shandong University & Albany Medical College.
Papers
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Journal ArticleDOI
ATF3 promotes erastin-induced ferroptosis by suppressing system Xc
Liyuan Wang,Liyuan Wang,Yichen Liu,Tingting Du,Tingting Du,Heng Yang,Lei Lei,Mengqi Guo,Han Fei Ding,Junran Zhang,Hongbo Wang,Xiaoguang Chen,Chunhong Yan +12 more
TL;DR: It is reported that activating transcription factor 3 (ATF3), a common stress sensor, can promote ferroptosis induced by erastin and add ATF3 to a short list of proteins that can regulate system Xc− and promote feroptosis repressed by this antiporter.
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A small-molecule inhibitor of MDMX activates p53 and induces apoptosis.
TL;DR: The identification of a benzofuroxan derivative that caused MCF-7 cells to undergo apoptosis and acted additively with nutlin-3a to activate p53 and decrease the viability of cancer cells shows that small molecules targeting MDMX expression would be of therapeutic benefits.
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TRPC channels: Structure, function, regulation and recent advances in small molecular probes.
Hongbo Wang,Xiaoding Cheng,Jinbin Tian,Yuling Xiao,Tian Tian,Fuchun Xu,Xuechuan Hong,Xuechuan Hong,Michael X. Zhu +8 more
TL;DR: Recent advancements in the understanding of TRPC channel regulation, structure, and discovery of novel TRPC small molecular probes over the past few years are covered, with the goal of facilitating drug discovery for the study ofTRPCs and therapeutic development.
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Near-Infrared II Dye-Protein Complex for Biomedical Imaging and Imaging-Guided Photothermal Therapy.
Xiaodong Zeng,Yuling Xiao,Jiacheng Lin,Shanshan Li,Hui Zhou,Jinxia Nong,Guozhen Xu,Hongbo Wang,Fuchun Xu,Junzhu Wu,Zixin Deng,Xuechuan Hong,Xuechuan Hong +12 more
TL;DR: It is the first time that the concept of light‐harvesting complex is exploited for enhancing the NIR‐II signals and photothermal energy conversion in molecule‐protein complex theranostic agent, making them a promising candidate for future clinical applications in cancer theranostics.
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H6, a novel hederagenin derivative, reverses multidrug resistance in vitro and in vivo.
Yanting Yang,Daokun Guan,Lei Lei,Jing Lu,Jia qi Liu,Gangqiang Yang,Chunhong Yan,Rong Zhai,Jingwei Tian,Yi Bi,Fenghua Fu,Hongbo Wang +11 more
TL;DR: H6 is a novel and potent MDR reversal agent, which has the potential to be administered in combination with conventional anticancer drugs and demonstrates robust reversal activity against MDR in vitro and in vivo.