Hongyan Wang

TL;DR: Examination of population substructures in a diverse set of over 1700 Han Chinese samples collected from 26 regions across China showed that most differentiated genes among clusters are involved in cardiac arteriopathy, and signals indicating significant differences among Han Chinese subpopulations should be carefully explained.

TL;DR: In this article, the authors conducted a genome-wide study of 1,000,000 genetic variants in 46 Tibetans and 92 Han Chinese (HAN) for identifying the signals of high-altitude adaptations (HAAs) in Tibetan genomes.

TL;DR: The data provide minimal evidence that the Val allele is a susceptibility factor for schizophrenia in either European or Asian populations.

TL;DR: The authors' experimental observations on human subjects and animal models strongly suggest that biallelic mutations in either CFAP43 or CFAP44 can cause sperm flagellar abnormalities and impair sperm motility.

TL;DR: Seven mutations in the primate-specific gene TUBB8 that were responsible for oocyte meiosis I arrest in 7 of the 24 families have dominant-negative effects that disrupt microtubule behavior and oocytes meiotic spindle assembly and maturation, causing female infertility.