I
Ian Todd
Researcher at University of Nottingham
Publications - 137
Citations - 6913
Ian Todd is an academic researcher from University of Nottingham. The author has contributed to research in topics: Tumor necrosis factor alpha & Exoplanet. The author has an hindex of 41, co-authored 137 publications receiving 6446 citations. Previous affiliations of Ian Todd include Queen's University Belfast & Queen's University.
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Germline mutations in the extracellular domains of the 55 kda tnf receptor, tnfr1, define a family of dominantly inherited autoinflammatory syndromes
Michael F. McDermott,Ivona Aksentijevich,Jérôme Galon,Elizabeth M. McDermott,B. William Ogunkolade,Michael Centola,Elizabeth Mansfield,Massimo Gadina,Leena Karenko,Tom Pettersson,John McCarthy,David M. Frucht,Martin Aringer,Yelizaveta Torosyan,Anna-Maija Teppo,Meredith Wilson,H.Mehmet Karaarslan,Ying Wan,Ian Todd,Geryl Wood,Ryan Schlimgen,Thisum R. Kumarajeewa,Sheldon M. Cooper,John P. Vella,Christopher I. Amos,John C. Mulley,Kathleen A. Quane,Michael G. Molloy,Annamari Ranki,Richard J. Powell,Graham A. Hitman,John J. O'Shea,Daniel L. Kastner +32 more
TL;DR: It is proposed that the autoinflammatory phenotype results from impaired downregulation of membrane TNFR1 and diminished shedding of potentially antagonistic soluble receptor inTNFR1-associated periodic syndromes.
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ELISA in the multiplex era: potentials and pitfalls
TL;DR: The challenges must be ameliorated prior to the widespread integration of multiplex immunoassays in clinical settings, which include biomarker validation, availability, stability, specificity and cross‐reactivity of reagents, and assay automation and the use of validated algorithms for transformation of raw data into diagnostic results.
Journal Article
Interferon-gamma induces HLA-DR expression by thyroid epithelium.
TL;DR: Recombinant human interferon-gamma (IFN-Gamma) induces expression of HLA-DR molecules on cultured human thyroid cells, whereas Namalva IFN-alpha, recombinant IFn-beta or recombinant interleukin-2 (IL-2) do not.
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The first WASP public data release
Oliver Butters,Richard G. West,David R. Anderson,A. Collier Cameron,Will Clarkson,B. Enoch,Carole A. Haswell,Coel Hellier,Keith Horne,Yogesh C. Joshi,Stephen R. Kane,Tim Lister,Pierre F. L. Maxted,N. R. Parley,Don Pollacco,Barry Smalley,Rachel Street,Ian Todd,Peter J. Wheatley,D. M. Wilson +19 more
TL;DR: The first public data release (DR1) of the WASP archive makes available all the light curve data and images from 2004 up to 2008 in both the Northern and Southern hemispheres.
Journal ArticleDOI
Organ-specific autoimmunity: a 1986 overview.
TL;DR: Progress in basic understanding of the disease processes should ultimately lead to more effective and specific means of therapeutic intervention, and may help to explain the heterogeneity of features and course of disease in different patients with the same underlying pathology.