In-Hyun Park

TL;DR: Compared to intravenous injections, IC transplantation is preferable to IV injection for delivery of hUC-MSCs during subacute phases of stroke, and IC-transplanted cells effectively improved behavioral deficits, serving to reduce infarct volumes and glial scar formation, increase subventricular counts of proliferating neuroblasts, and promote cerebrovascular ingrowth in ischemic penumbra regions.

TL;DR: The use of iPSCs to generate hematopoietic stem/progenitor cells (HSPC) is of considerable therapeutic interest, as allogeneic HSPC transplantation is limited by the lack of compatible donors, a high risk of engraftment failure and GVHD.

TL;DR: In this article, the authors used microRNA mimicking miR-208b-3p, ascorbic acid and bone morphogenetic protein 4 to reprogram mouse tail-tip fibroblasts into three cell types: cardiomyocytes, endothelial cells or smooth muscle cells.

TL;DR: The characterization of XCR is reviewed, and the key regulators involved in XCI are reviewed for their role in suppressing the active histone marks and the genes in the active chromosome for their inhibition of X inactivation signals.

TL;DR: In this paper, the authors highlight recent advances of neuronal organoid technologies, focusing on the region-specific brain organoids and complementation with endothelial cells and microglia, and discuss their potential applications to neuronal diseases.