I
Ivan Kalina
Publications - 33
Citations - 2906
Ivan Kalina is an academic researcher. The author has contributed to research in topics: DNA adduct & Environmental exposure. The author has an hindex of 22, co-authored 33 publications receiving 2827 citations.
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Journal Article
Metabolic gene polymorphism frequencies in control populations.
Seymour Garte,Laura Gaspari,A.-K. Alexandrie,Christine B. Ambrosone,Herman Autrup,Judith L. Autrup,H. Baranova,L. Bathum,Simone Benhamou,Paolo Boffetta,C. Bouchardy,K. Breskvar,J. Brockmöller,Ingolf Cascorbi,Margie L. Clapper,Christiane Coutelle,Ann K. Daly,Marco Dell'Omo,Vita Dolzan,C.M. Dresler,Anthony A. Fryer,Aage Haugen,David W. Hein,Allan Hildesheim,Ari Hirvonen,L.L. Hsieh,Magnus Ingelman-Sundberg,Ivan Kalina,Daehee Kang,Masahiro Kihara,Chikako Kiyohara,Pierre Kremers,Philip Lazarus,Loic Le Marchand,Maria Celeste Lechner,E.M.M. van Lieshout,Stephanie J. London,Johannes J. Manni,Christine Maugard,S. Morita,Valle Nazar-Stewart,K. Noda,Yoshio Oda,Fritz F. Parl,Roberta Pastorelli,I. Persson,Wilbert H.M. Peters,Agneta Rannug,Timothy R. Rebbeck,Angela Risch,L. Roelandt,Marjorie Romkes,David Ryberg,Salagovic J,Bernadette Schoket,Janeric Seidegård,Peter G. Shields,Edith Sim,D. Sinnet,Richard C. Strange,Isabelle Stücker,Haruhiko Sugimura,Jordi To-Figueras,Paolo Vineis,M.C. Yu,Emanuela Taioli +65 more
TL;DR: Using the International Project on Genetic Susceptibility to Environmental Carcinogens (GSEC) database containing information on over 15,000 control (noncancer) subjects, the allele and genotype frequencies for many of the more commonly studied metabolic genes in the human population were determined.
Journal ArticleDOI
Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk
Simone Benhamou,Won Jin Lee,A.-K. Alexandrie,Paolo Boffetta,Christine Bouchardy,Dorota Butkiewicz,Jürgen Brockmöller,Margie L. Clapper,Ann K. Daly,Vita Dolzan,Jean G. Ford,Laura Gaspari,Aage Haugen,Ari Hirvonen,Kirsti Husgafvel-Pursiainen,Magnus Ingelman-Sundberg,Ivan Kalina,Masahiro Kihara,Pierre Kremers,Loic Le Marchand,Stephanie J. London,Valle Nazar-Stewart,Masako Onon-Kihara,Agneta Rannug,Marjorie Romkes,David Ryberg,Janeric Seidegård,Peter G. Shields,Richard C. Strange,Isabelle Stücker,Jordi To-Figueras,Paul Brennan,Emanuela Taioli +32 more
TL;DR: A pooled analysis of the original data of about 9500 subjects involved in 21 case-control studies from the International Collaborative Study on Genetic Susceptibility to Environmental Carcinogens (GSEC) data set was performed to assess the role of GSTM1 genotype as a modifier of the effect of smoking on lung cancer risk with adequate power.
Journal ArticleDOI
Pooled Analysis and Meta-analysis of Glutathione S-Transferase M1 and Bladder Cancer: A HuGE Review
Lawrence S. Engel,Emanuela Taioli,Ruth M. Pfeiffer,Montserrat Garcia-Closas,Pamela M. Marcus,Qing Lan,Paolo Boffetta,Paolo Vineis,Herman Autrup,Douglas A. Bell,Robert A. Branch,Jürgen Brockmöller,Ann K. Daly,Susan R. Heckbert,Ivan Kalina,Daehee Kang,Takahiko Katoh,Amalia Lafuente,Henry J. Lin,Marjorie Romkes,Jack A. Taylor,Nathaniel Rothman +21 more
TL;DR: Meta- and pooled analyses of published and unpublished, case-control, genotype-based studies that examined the association between GSTM1 null status and bladder cancer indicate that, among populations studied to date, GSTM 1 null status is associated with a modest increase in the risk of bladder cancer.
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CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: a pooled analysis.
Rayjean J. Hung,Paolo Boffetta,Jürgen Brockmöller,Dorota Butkiewicz,Ingolf Cascorbi,Margie L. Clapper,Seymour Garte,Aage Haugen,Ari Hirvonen,Sisko Anttila,Ivan Kalina,Loic Le Marchand,Stephanie J. London,Agneta Rannug,Marjorie Romkes,Salagovic J,Bernadette Schoket,Laura Gaspari,Emanuela Taioli +18 more
TL;DR: It is suggested that the CYP1A1 Ile(462)Val variant allele might play a role in lung carcinogenesis among non-smokers, possibly in combination with the GSTM1 null genotype.
Journal ArticleDOI
Molecular epidemiology studies of carcinogenic environmental pollutants. Effects of polycyclic aromatic hydrocarbons (PAHs) in environmental pollution on exogenous and oxidative DNA damage.
Peter B. Farmer,Rajinder Singh,Balvinder Kaur,Radim J. Sram,Blanka Binkova,Ivan Kalina,Todor A. Popov,Seymour Garte,Emanuela Taioli,Alena Gábelová,Antonina Cebulska-Wasilewska +10 more
TL;DR: An investigation of populations exposed to environmental pollution in three European countries, Czech Republic, Slovak Republic and Bulgaria, pays particular attention to PAHs, but also investigates the extent of radically induced DNA damage in the exposed populations.