C
Christine Maugard
Researcher at Université de Montréal
Publications - 61
Citations - 7514
Christine Maugard is an academic researcher from Université de Montréal. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 27, co-authored 60 publications receiving 7120 citations. Previous affiliations of Christine Maugard include University of Nantes & University of Strasbourg.
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Journal ArticleDOI
Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families
D Ford,Douglas F. Easton,Michael R. Stratton,Steven A. Narod,David E. Goldgar,Peter Devilee,D. T. Bishop,Barbara L. Weber,Gilbert M. Lenoir,Jenny Chang-Claude,Hagay Sobol,M D Teare,Jeffery P. Struewing,Adalgeir Arason,Siegfried Scherneck,Julian Peto,Timothy R. Rebbeck,Patricia N. Tonin,Susan L. Neuhausen,Rosa B. Barkardottir,Jorunn E. Eyfjord,Henry T. Lynch,Bruce A.J. Ponder,Simon A. Gayther,J.M. Birch,Annika Lindblom,Dominique Stoppa-Lyonnet,Y. J. Bignon,Åke Borg,U Hamann,Neva E. Haites,Rodney J. Scott,Christine Maugard,Hans F. A. Vasen,Susanne Seitz,Lisa A. Cannon-Albright,Andrew Craig Schofield,Moraima Zelada-Hedman +37 more
TL;DR: The lifetime risk of breast cancer appears similar to the risk in BRCA1 carriers, but there was some suggestion of a lower risk in bRCA2 carriers <50 years of age.
Journal Article
Metabolic gene polymorphism frequencies in control populations.
Seymour Garte,Laura Gaspari,A.-K. Alexandrie,Christine B. Ambrosone,Herman Autrup,Judith L. Autrup,H. Baranova,L. Bathum,Simone Benhamou,Paolo Boffetta,C. Bouchardy,K. Breskvar,J. Brockmöller,Ingolf Cascorbi,Margie L. Clapper,Christiane Coutelle,Ann K. Daly,Marco Dell'Omo,Vita Dolzan,C.M. Dresler,Anthony A. Fryer,Aage Haugen,David W. Hein,Allan Hildesheim,Ari Hirvonen,L.L. Hsieh,Magnus Ingelman-Sundberg,Ivan Kalina,Daehee Kang,Masahiro Kihara,Chikako Kiyohara,Pierre Kremers,Philip Lazarus,Loic Le Marchand,Maria Celeste Lechner,E.M.M. van Lieshout,Stephanie J. London,Johannes J. Manni,Christine Maugard,S. Morita,Valle Nazar-Stewart,K. Noda,Yoshio Oda,Fritz F. Parl,Roberta Pastorelli,I. Persson,Wilbert H.M. Peters,Agneta Rannug,Timothy R. Rebbeck,Angela Risch,L. Roelandt,Marjorie Romkes,David Ryberg,Salagovic J,Bernadette Schoket,Janeric Seidegård,Peter G. Shields,Edith Sim,D. Sinnet,Richard C. Strange,Isabelle Stücker,Haruhiko Sugimura,Jordi To-Figueras,Paolo Vineis,M.C. Yu,Emanuela Taioli +65 more
TL;DR: Using the International Project on Genetic Susceptibility to Environmental Carcinogens (GSEC) database containing information on over 15,000 control (noncancer) subjects, the allele and genotype frequencies for many of the more commonly studied metabolic genes in the human population were determined.
Journal ArticleDOI
Prediction of BRCA1 Status in Patients with Breast Cancer Using Estrogen Receptor and Basal Phenotype
Sunil R. Lakhani,Jorge S. Reis-Filho,L G Fulford,Frédérique Penault-Llorca,Marc van der Vijver,Suzanne Parry,Timothy Bishop,Javier Benitez,Rivas C,Yves-Jean Bignon,Jenny Chang-Claude,Ute Hamann,Cees J. Cornelisse,Peter Devilee,Matthias W. Beckmann,Carolin Nestle-Krämling,Peter A. Daly,Neva E. Haites,Jenny Varley,Fiona Lalloo,G Evans,Christine Maugard,Hanne Meijers-Heijboer,Jan G. M. Klijn,Edith Olah,Barry A. Gusterson,Silvana Pilotti,Paolo Radice,Siegfried Scherneck,Hagay Sobol,Jocelyne Jacquemier,Teresa Wagner,Julian Peto,Michael R. Stratton,Lesley McGuffog,Douglas F. Easton +35 more
TL;DR: The use of cytokeratin staining in combination with ER and morphology provides a more accurate predictor of BRCA1 mutation status than previously available, that may be useful in selecting patients for BRCa1 mutation testing.
Journal ArticleDOI
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
Corine Bertolotto,Fabienne Lesueur,Sandy Giuliano,Thomas Strub,Mahaut de Lichy,Karine Bille,Philippe Dessen,Benoit d’Hayer,Hamida Mohamdi,Audrey Remenieras,Eve Maubec,Arnaud de la Fouchardière,Vincent Molinié,Pierre Vabres,Stéphane Dalle,N. Poulalhon,Tanguy Martin-Denavit,Luc Thomas,Pascale Andry-Benzaquen,Nicolas Dupin,F. Boitier,Annick Rossi,Jean-Luc Perrot,Bruno Labeille,Caroline Robert,Bernard Escudier,Olivier Caron,Laurence Brugières,Simon Saule,Betty Gardie,Sophie Gad,Stéphane Richard,Jérôme Couturier,Bin Tean Teh,Paola Ghiorzo,Lorenza Pastorino,Susana Puig,Celia Badenas,Håkan Olsson,Christian Ingvar,Etienne Rouleau,Rosette Lidereau,Philippe Bahadoran,Philippe Vielh,Eve Corda,Hélène Blanché,Diana Zelenika,Pilar Galan,François Aubin,Bertrand Bachollet,Celine Becuwe,Pascaline Berthet,Yves-Jean Bignon,Valérie Bonadona,Jean -Louis Bonafe,Marie -Noelle Bonnet-Dupeyron,Frédéric Cambazard,Jacqueline Chevrant-Breton,Isabelle Coupier,Sophie Dalac,Liliane Demange,Michel D'Incan,Catherine Dugast,Laurence Faivre,Lynda Vincent-Fetita,Marion Gauthier-Villars,Brigitte Gilbert,Florent Grange,Jean-Jacques Grob,Philippe Humbert,Nicolas Janin,Pascal Joly,Delphine Kerob,Christine Lasset,Dominique Leroux,Julien Levang,Jean -Marc Limacher,Cristina Bulai Livideanu,Michel Longy,Alain Lortholary,Dominique Stoppa-Lyonnet,Sandrine Mansard,Ludovic Mansuy,Karine Marrou,Christine Mateus,Christine Maugard,Nicolas Meyer,Catherine Noguès,Pierre Souteyrand,Laurence Venat-Bouvet,Hélène Zattara,Valérie Chaudru,Gilbert M. Lenoir,Mark Lathrop,Irwin Davidson,Marie-Françoise Avril,Florence Demenais,Robert Ballotti,Brigitte Bressac-de Paillerets +98 more
TL;DR: A germline missense substitution in MITF (Mi-E318K) is identified that occurred at a significantly higher frequency in genetically enriched patients affected with melanoma, RCC or both cancers, when compared with controls and provides insights into the link between SUMOylation, transcription and cancer.
Journal ArticleDOI
International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers.
Kelly A. Metcalfe,Daphna Birenbaum-Carmeli,Jan Lubinski,Jacek Gronwald,Henry T. Lynch,Pål Møller,Parviz Ghadirian,William D. Foulkes,Jan Klijn,Eitan Friedman,Eitan Friedman,Charmaine Kim-Sing,Peter Ainsworth,B. Rosen,Susan M. Domchek,T Wagner,Nadine Tung,Siranoush Manoukian,Fergus J. Couch,Ping Sun,Steven A. Narod,M. Daly,Howard M. Saal,Kevin Sweet,Dominique Stoppa Lyonnet,A. Eisen,G. Rennen,J. McLennan,Ruth Gershoni-Baruch,Judy Garber,Shelly Cummings,J. N. Weitzel,Beth Y. Karlan,Raluca N. Kurz,Wendy McKinnon,Marie E. Wood,Dawna Gilchrist,Albert E. Chudley,Michael P. Osborne,David A. Fishman,W. S. Meschino,Edmond G. Lemire,Christine Maugard,Gordon B. Mills,Sofia D. Merajver,Daniel Rayson,J. M. Collee +46 more
TL;DR: Nearly one‐half of the women at risk for breast cancer had taken no preventive option, relying solely on screening, and there were large differences in the uptake of the different preventive options by country of residence.