J. P. Beressi

TL;DR: Evidence is reported for the localization of a previously undetected suscept-ibility locus for IDDM in the region of the FGF3 gene on chromo-some llq, showing the potential of genome-wide linkage studies to detect susceptibility loci in IDDM and other multifactor-ial disorders.

TL;DR: The use of polymerase chain reaction (PCR) and sequence specific oligonucleotide analysis (SSO) to identify DQA1, DQB1, and DRB1 alleles, haplotypes and genotypes in Algerian patients suggest that theDRB1*0405 allele which encodes an Asp57‐negative β chain may contribute to IDDM susceptibility in a similar way as Asp 57‐negative DQβ chains.

TL;DR: In this article , the authors developed a Master Protocol, based on the "backbone" of the INNODIA natural history study, which could improve the delivery of phase 2 studies exploring the use of single or combinations of Investigational Medicinal Products (IMPs), designed to prevent or reverse declines in beta-cell function in individuals with newly diagnosed type 1 diabetes.

TL;DR: In this paper , the authors used linear mixed-effects modeling on RNA-seq data to identify genes associated with age, sex, or disease progression in patients with recent-onset type 1 diabetes.