L
L. Gommers
Publications - 14
Citations - 381
L. Gommers is an academic researcher. The author has contributed to research in topics: Medicine & Immunology. The author has an hindex of 5, co-authored 14 publications receiving 381 citations.
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Journal ArticleDOI
Divergent SARS CoV-2 Omicron-reactive T- and B cell responses in COVID-19 vaccine recipients
Corine H. GeurtsvanKessel,D. Geers,Katharina S. Schmitz,Anna Z Mykytyn,Mart M. Lamers,Susanne Bogers,Sandra M.J. Scherbeijn,L. Gommers,Roos S G Sablerolles,N. Nieuwkoop,Laurine C Rijsbergen,Laura J. A. van Dijk,J. de Wilde,Kimberley Alblas,Tim I Breugem,Bart J. A. Rijnders,Herbert de Jager,Daniela Weiskopf,P. H. M. van der Kuy,Alessandro Sette,Marion Koopmans,Alba Grifoni,Bart L. Haagmans,Rory D. de Vries +23 more
TL;DR: This study shows that vaccinated individuals retain T cell immunity to the SARS-CoV-2 Omicron variant, potentially balancing the lack of neutralizing antibodies in preventing or limiting severe COVID-19 cases.
Journal ArticleDOI
Immunogenicity of the mRNA-1273 COVID-19 vaccine in adult patients with inborn errors of immunity
Leanne P M van Leeuwen,Corine H. GeurtsvanKessel,Pauline M. Ellerbroek,Godelieve J. de Bree,Judith Potjewijd,Abraham Rutgers,Hetty Jolink,Frank L. van de Veerdonk,Eric C. M. van Gorp,F. de Wilt,Susanne Bogers,L. Gommers,D. Geers,Anke H W Bruns,Helen L. Leavis,Jelle W. van Haga,Bregtje A. Lemkes,Annelou L.I.P. van der Veen,S.F.J. de Kruijf-Bazen,Pieter van Paassen,Karina de Leeuw,Annick A. J. M. van de Ven,Petra H. Verbeek-Menken,Annelies van Wengen,Sandra M. Arend,Anja J. Ruten-Budde,Marianne W. van der Ent,P. M. van Hagen,Rogier W. Sanders,Marloes Grobben,Karlijn van der Straten,Judith A. Burger,Meliawati Poniman,Stefan Nierkens,Marit J. van Gils,Rory D. de Vries,Virgil A. S. H. Dalm +36 more
TL;DR: In a prospective, controlled, multicenter study, 505 patients with inborn errors of immunity (IEI) (CVID), isolated or undefined antibody deficiencies, X-linked agammaglobulinemia, combined B- and T-cell immunodeficiency, phagocyte defects, and 192 controls were included as discussed by the authors .
Journal ArticleDOI
Alternative strategies to increase the immunogenicity of COVID-19 vaccines in kidney transplant recipients not responding to two or three doses of an mRNA vaccine (RECOVAC): a randomised clinical trial
Marcia M. L. Kho,A. Lianne Messchendorp,S. C. Frölke,C. Imhof,Vera Jch Koomen,S. R. K. Malahe,Priya Vart,D. Geers,Rory D. de Vries,Corine H. GeurtsvanKessel,Carla C. Baan,Renate G. van der Molen,Dimitri A. Diavatopoulos,Ester B. M. Remmerswaal,Debbie van Baarle,Rob van Binnendijk,Gerco den Hartog,Aiko P. J. de Vries,Ron T. Gansevoort,Frederike J. Bemelman,Marlies E.J. Reinders,Jan-Stephan F. Sanders,Luuk B. Hilbrands,Alferso C. Abrahams,Marije C. Baas,P. Bouwmans,M A G J ten Dam,L. Gommers,Dorien Standaar,Marieke van der Heiden,Yvonne Adema,Marieken J. Boer-Verschragen,Wouter B Mattheussens,Ria L. A. Philipsen,Djenolan Van Mourik,Susanne Bogers,Laura J. A. van Dijk,Nynke Y. Rots,Gaby Smits,Marjan Kuijer,Marc H Hemmelder +40 more
TL;DR: Repeated vaccination increases SARS-CoV-2-specific antibodies in KTRs, without further enhancement by use of a higher dose, a heterologous vaccine, or 2 weeks discontinuation of mycophenolate mofetil or mycopenolic acid.
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INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes
David B. Dunger,Sylvaine F. A. Bruggraber,Adrian Mander,M. Loredana Marcovecchio,Timothy Tree,Piotr Jaroslaw Chmura,Mikael Knip,Anke M. Schulte,Chantal Mathieu,Cyril Mathieu,Pieter Gillard,Kristina Casteels,Lutgart Overbergh,Clarissa Wallace,M. Evans,Ajay Thankamony,Emile Hendriks,Sfa Bruggraber,Mark Peakman,Noel G. Morgan,Steven Richardson,J. Todd,Linda S. Wicker,Colin M. Dayan,Mohammad Alhadj Ali,Thomas R. Pieber,DL Eizirik,Miriam Cnop,Soeren Brunak,Flemming Pociot,Jesper Johannesen,Peter Rossing,C. Legido Quigley,Roberto Mallone,Raphael Scharfmann,Christian Boitard,Timo Otonkoski,Riitta Veijola,Riitta Lahesmaa,M. Oresic,Jorma Toppari,Thomas Danne,AG Ziegler,Peter Achenbach,Teresa Rodriguez-Calvo,Michele Solimena,Ezio Bonifacio,Sandra Speier,R.W. Holl,Francesco Dotta,Francesco Chiarelli,Paula M Marchetti,Emanuele Bosi,Stefano Cianfarani,Paolo Ciampalini,C De Beaufort,Knut Dahl-Jørgensen,Torild Skrivarhaug,Geir Joner,Lars Krogvold,Przemysława Jarosz-Chobot,Tadej Battelino,Bernard Thorens,Martin Gotthardt,Bart O. Roep,T. Nikolic,Arnaud Zaldumbide,Åke Lernmark,Markus Lundgren,G. Costecalde,Thorsten Strube,Amanda Schulte,Achim Dipl Ing Nitsche,Matthias von Herrath,J Wesley,A Napolitano-Rosen,Matthias H. Thomas,N. C. Schloot,Allison B. Goldfine,Frank Waldron-Lynch,Jill E. Kompa,Aruna Vedala,Nina Hartmann,Gemma Muñiz Nicolás,Jean Van Rampelbergh,Nicolas Bovy,S. Dutta,J. Soderberg,F. Martin,Gina Agiostratidou,Anne Koralova,Rene Willemsen,A. Smith,B Anand,V Puthi,Sagen Zac-Varghese,Vishnu Datta,Rayanne Soraia Aguiar de Melo Dias,R. Sundaram,Bina Vaidya,CJ Patterson,Klara Owen,Bruno Piel,Schott Heller,TR Randell,T Gazis,E. Bismuth Reismen,Jean-Claude Carel,J.P. Riveline,Jean-François Gautier,F. Andreelli,F. Travert,Emmanuel Cosson,Alfred Penfornis,Catherine Petit,Benoit Feve,Nadine Lucidarme,J. P. Beressi,Catherine C. Ajzenman,A Radu,S. Greteau-Hamoumou,Cecile Bibal,T. Meißner,Bettina Heidtmann,Sonia Toni,Birgit Rami-Merhar,Bart Eeckhout,Bernard Peene,N. Vantongerloo,Toon Maes,L. Gommers,Juan Vela,Esther Latres +132 more
TL;DR: In this article , the authors developed a Master Protocol, based on the "backbone" of the INNODIA natural history study, which could improve the delivery of phase 2 studies exploring the use of single or combinations of Investigational Medicinal Products (IMPs), designed to prevent or reverse declines in beta-cell function in individuals with newly diagnosed type 1 diabetes.
Journal ArticleDOI
Ad26.COV2.S priming provided a solid immunological base for mRNA-based COVID-19 booster vaccination
D. Geers,Roos S G Sablerolles,Debbie van Baarle,Neeltje A. Kootstra,Wim J. R. Rietdijk,Katharina S. Schmitz,L. Gommers,Susanne Bogers,Nella J. Nieuwkoop,Laura J. A. van Dijk,Eva van Haren,Melvin Lafeber,Virgil A. S. H. Dalm,Abraham Goorhuis,Douwe F. Postma,Leo G. Visser,Anke Huckriede,Alessandro Sette,Alba Grifoni,Rik L. de Swart,Marion Koopmans,P. H. M. van der Kuy,Corine H. GeurtsvanKessel,Rory D. de Vries +23 more
TL;DR: In this article , the authors performed immunological profiling of Ad26.COV2.S-primed individuals before and after homologous or heterologous (mRNA-1273 or BNT162b2) booster vaccination.