J
James Arthos
Researcher at National Institutes of Health
Publications - 141
Citations - 13478
James Arthos is an academic researcher from National Institutes of Health. The author has contributed to research in topics: T cell & Antibody. The author has an hindex of 52, co-authored 134 publications receiving 12693 citations. Previous affiliations of James Arthos include Columbia University & Government of the United States of America.
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Journal ArticleDOI
Correction for Lu et al., "Shedding-Resistant HIV-1 Envelope Glycoproteins Adopt Downstream Conformations That Remain Responsive to Conformation-Preferring Ligands".
Maolin Lu,Xiaochu Ma,Nick Reichard,Daniel S. Terry,James Arthos,Amos B. Smith,Joseph Sodroski,Scott C. Blanchard,Walther Mothes +8 more
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Evidence of recurrent selection of mutations commonly found in SARS-CoV-2 variants of concern in viruses infecting immunocompromised patients
Lívia R. Góes,Juliana D. Siqueira,Marianne M. Garrido,Brunna M. Alves,Claudia Cicala,James Arthos,João P. B. Viola,Marcelo A. Soares +7 more
TL;DR: A SARS-CoV-2+ cancer patient from the beginning of the COVID-19 pandemic whose virus quasispecies across multiple timepoints carried several immune escape mutations found in more contemporary VOC that appeared to be selected for during infection are reported.
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Neutralizing and Targeting Properties of a New Set of α4β7-Specific Antibodies Are Influenced by Their Isotype.
Alexandre Girard,Katija Jelicic,Don Van Ryk,Nicolas Rochereau,Claudia Cicala,James Arthos,Blandine Noailly,Christian Genin,Bernard Verrier,Stephanie Laurant,Diane Razanajaoana-Doll,Jean-Jacques Pin,Stéphane Paul +12 more
TL;DR: An improved immunization strategy based on an innovative selection process is designed and applied to isolate new lymphocyte–specific monoclonal antibodies that are able to prevent their migration into inflamed gut tissues and/or to counteract HIV infection in vitro.
Journal ArticleDOI
The Genetic Analysis of the HIV Envelope Binding Domain on CD4
James Arthos,Keith Charles Deen,Allan R. Shatzman,Alemseged Truneh,Martin Rosenberg,Raymond W. Sweet +5 more
TL;DR: It is concluded that amino acids at both the amino and carboxy termini are critical to the conformation of the V1 domain and, in particular, to the integrity of the gp120 binding site.
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Selective transmission of some HIV-1 subtype C variants might depend on Envelope stimulating dendritic cells to secrete IL-10
Evelyn Ngwa Lumngwena,Bianca Abrahams,Liliwe Shuping,Claudia Cicala,James Arthos,Zenda Woodman +5 more
TL;DR: These findings suggest that nuanced differences in binding of TF Env to DC-SIGN might trigger alternative DC immune responses in the female genital tract (FGT) that favour HIV-1 survival and facilitate transmission.