M
Marcelo A. Soares
Researcher at Federal University of Rio de Janeiro
Publications - 160
Citations - 4367
Marcelo A. Soares is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Drug resistance & Virus. The author has an hindex of 31, co-authored 146 publications receiving 3803 citations. Previous affiliations of Marcelo A. Soares include Rio de Janeiro Federal Institute of Education, Science and Technology & University of Alabama at Birmingham.
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Journal ArticleDOI
Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration
Rami Kantor,David Katzenstein,Brad Efron,Ana Patricia Carvalho,Brian Wynhoven,Patricia A. Cane,John R. Clarke,Sunee Sirivichayakul,Marcelo A. Soares,Joke Snoeck,Candice Pillay,H Rudich,Rosangela Rodrigues,África Holguín,Koya Ariyoshi,María Belén Bouzas,Pedro Cahn,Wataru Sugiura,Vincent Soriano,Luís Fernando de Macedo Brígido,Z Grossman,Lynn Morris,Anne-Mieke Vandamme,Amilcar Tanuri,Praphan Phanuphak,Jonathan Weber,Deenan Pillay,P. Richard Harrigan,Ricardo Jorge Camacho,Jonathan M. Schapiro,Robert W. Shafer +30 more
TL;DR: Global surveillance and genotypic assessment of drug resistance should focus primarily on the known subtype B drug-resistance mutations.
Journal ArticleDOI
Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis
Soo-Yon Rhee,José Luis Santiago Blanco,Michael R. Jordan,Jonathan Taylor,Philippe Lemey,Vici Varghese,Raph L. Hamers,Silvia Bertagnolio,Tobias F. Rinke de Wit,Avelin F. Aghokeng,Jan Albert,Radko Avi,Santiago Ávila-Ríos,Pascal O. Bessong,James Brooks,Charles A. Boucher,Zabrina L. Brumme,Michael P. Busch,Hermann Bussmann,Marie Laure Chaix,Bum Sik Chin,Toni T. D’Aquin,Cillian De Gascun,Anne Derache,Diane Descamps,Alaka Deshpande,Cyrille F. Djoko,Susan H. Eshleman,Hervé Fleury,Pierre Frange,Seiichiro Fujisaki,P. Richard Harrigan,Junko Hattori,África Holguín,Gillian Hunt,Hiroshi Ichimura,Pontiano Kaleebu,David Katzenstein,Sasisopin Kiertiburanakul,Jerome H. Kim,Sung Soon Kim,Yanpeng Li,Irja Lutsar,Lynn Morris,Nicaise Ndembi,Kee Peng Ng,Ramesh S. Paranjape,Martine Peeters,Mario Poljak,Matthew Price,Manon Ragonnet-Cronin,Gustavo Reyes-Terán,Morgane Rolland,Sunee Sirivichayakul,Davey M. Smith,Marcelo A. Soares,Vincent Soriano,Deogratius Ssemwanga,Maja Stanojevic,Mariane A. Stefani,Wataru Sugiura,Somnuek Sungkanuparph,Amilcar Tanuri,Kok Keng Tee,Hong-Ha M. Truong,David A. M. C. van de Vijver,Nicole Vidal,Chunfu Yang,Rongge Yang,Gonzalo Yebra,John P. A. Ioannidis,Anne-Mieke Vandamme,Robert W. Shafer +72 more
TL;DR: Most TDR strains in SSA and SSEA arose independently, suggesting that ARV regimens with a high genetic barrier to resistance combined with improved patient adherence may mitigate TDR increases by reducing the generation of new ARV-resistant strains.
Journal ArticleDOI
Global and regional molecular epidemiology of HIV-1, 1990–2015: a systematic review, global survey, and trend analysis
Joris Hemelaar,Ramyiadarsini Elangovan,Jason Yun,Leslie Dickson-Tetteh,Isabella Fleminger,Shona Kirtley,Brian G. Williams,Eleanor Gouws-Williams,Peter D. Ghys,Alash'le Abimiku,Simon Agwale,Chris P. Archibald,Boaz Avidor,María Gabriela Barbás,Françoise Barré-Sinoussi,Banson Barugahare,El Hadj Belabbes,Silvia Bertagnolio,Deborah L. Birx,Aleksei F Bobkov,James Brandful,Helba Bredell,Catherine A. Brennan,James Brooks,Marie Bruckova,Luigi Buonaguro,Franco M. Buonaguro,Stefano Buttò,Anne Buvé,Mary S. Campbell,Jean K. Carr,Alex Carrera,Manuel Gómez Carrillo,Connie Celum,Beth Chaplin,Macarthur Charles,Dimitrios Chatzidimitriou,Zhiwei Chen,Katsumi Chijiwa,David Cooper,Philip Cunningham,Anoumou Y. Dagnra,Cillian De Gascun,Julia del Amo,Elena Delgado,Ursula Dietrich,Dominic M. Dwyer,Dennis Ellenberger,Barbara Ensoli,Max Essex,Feng Gao,Hervé Fleury,Peter N. Fonjungo,Vincent Foulongne,Deepak A Gadkari,Federico García,Roger Garsia,Guy Michel Gershy-Damet,Judith R. Glynn,Ruth Goodall,Zehava Grossman,Monick Lindenmeyer-Guimarães,Beatrice H. Hahn,Raph L. Hamers,Osamah Hamouda,Ray Handema,Xiang He,Joshua T. Herbeck,David D. Ho,África Holguín,Mina C. Hosseinipour,Gillian Hunt,Masahiko Ito,Mohamed Ali Bel Hadj Kacem,Erin M. Kahle,Pontiano Kaleebu,Marcia L. Kalish,Adeeba Kamarulzaman,Chun Kang,Phyllis J. Kanki,Edward Karamov,Jean-Claude Karasi,Kayitesi Kayitenkore,Tony Kelleher,Dwip Kitayaporn,Leondios G. Kostrikis,Claudia Kücherer,Claudia Lara,Thomas Leitner,Kirsi Liitsola,J.R. Lingappa,Marek Linka,Ivette Lorenzana de Rivera,Vladimir Lukashov,Shlomo Maayan,Luzia Mayr,Francine E. McCutchan,Nicolas Meda,Elisabeth Menu,Fred Mhalu,Doreen Mloka,John L. Mokili,Brigitte Montes,Orna Mor,Mariza G. Morgado,Fausta Mosha,Awatef Moussi,James I. Mullins,Rafael Nájera,Mejda Nasr,Nicaise Ndembi,Joel R. Neilson,Vivek R. Nerurkar,Florian Neuhann,Claudine Nolte,Vlad Novitsky,Philippe Nyambi,Marianna Ofner,Fem J Paladin,Anna Papa,Jean Pape,Neil Parkin,Christopher M. Parry,Martine Peeters,Alexandra Pelletier,Lucía Pérez-Álvarez,Deenan Pillay,Angie N Pinto,Trinh Duy Quang,Cecilia Rademeyer,Filimone Raikanikoda,Mark A. Rayfield,Jean-Marc Reynes,Tobias F. Rinke de Wit,Kenneth E. Robbins,Morgane Rolland,Christine Rousseau,Jesus Salazar-Gonzales,Hanan Salem,Mika Salminen,Horacio Salomon,Paul Sandstrom,Mario L. Santiago,Abdoulaye Dieng Sarr,Bryan Schroeder,Michel Segondy,Philippe Selhorst,Sylvester Sempala,Jean Servais,Ansari Shaik,Yiming Shao,Amine Slim,Marcelo A. Soares,Elijah M. Songok,Debbie Stewart,Julie Stokes,Shambavi Subbarao,Ruengpung Sutthent,Jun Takehisa,Amilcar Tanuri,Kok Keng Tee,Kiran Thapa,Michael M. Thomson,Tyna Tran,Willy Urassa,Hiroshi Ushijima,Philippe Van de Perre,Guido van der Groen,Kristel Van Laethem,Joep J. van Oosterhout,Ard van Sighem,Eric Van Wijngaerden,Anne-Mieke Vandamme,Jurgen Vercauteren,Nicole Vidal,Lesley Wallace,Carolyn Williamson,Dawit Wolday,Jianqing Xu,Chunfu Yang,Linqi Zhang,Rong Zhang +181 more
TL;DR: The distribution of HIV-1 subtypes and recombinants changed over time in countries, regions, and globally as well as at a global level during 2005-15, where subtype B increased, subtypes A and D were stable, and subtypes C and G and CRF02_AG decreased.
Journal ArticleDOI
Human Papillomavirus E6 Triggers Upregulation of the Antiviral and Cancer Genomic DNA Deaminase APOBEC3B
Valdimara C Vieira,Brandon Leonard,Elizabeth A. White,Gabriel J. Starrett,Nuri A. Temiz,Laurel D. Lorenz,Denis Lee,Marcelo A. Soares,Paul F. Lambert,Peter M. Howley,Reuben S. Harris +10 more
TL;DR: The hypothesis that human papillomavirus (HPV) infection causes A3B upregulation is tested and a model in which high-risk HPV E6, possibly through functional inactivation of TP53, causes derepression of A3 B gene transcription and elevated A2B enzyme levels is suggested.
Journal ArticleDOI
The regulation of primate immunodeficiency virus infectivity by Vif is cell species restricted: a role for Vif in determining virus host range and cross‐species transmission
James H. M. Simon,David L. Miller,Ron A. M. Fouchier,Marcelo A. Soares,Keith Peden,Michael H. Malim +5 more
TL;DR: Using human cells as virus producers, it was found that the HIV‐1 Vif protein could modulate the infectivity of HIV-1 itself, HIV‐2 and SIV isolated from African green monkeys (SIVAGM) and the finding that the replication of murine leukemia virus could also be stimulated by HIV‐ 1 Vif expression in human cells further supported this notion.