James D. Young

TL;DR: Exposure of site-bound [3H]nitrobenzylthioinosine to high intensity U.V. light resulted in the photoaffinity labelling of lung proteins with apparent molecular weights similar to that of the human erythrocyte nucleoside transporter (45,000-65,000).

TL;DR: Inosine is a major physiological energy source of pig erythrocytes and cells 'protected' themselves against some of the consequences of deprivation of energy substrate by glycolyzing the ribose moiety of inosine produced during ATP catabolism.

TL;DR: A helical wheel projection of TM 8 predicted that Phe-334 and Asn-338 lie in close proximity to other highly conserved and/or hydrophilic residues, suggesting that they form part of a structurally important region that influences interactions with inhibitors, protein folding, and rates of conformational change during the transport cycle.

TL;DR: Selenite and tellurite-induced haemolysis therefore provides a simple method for detecting GSH-deficient cells and the lytic effect of selenite may explain some of the symptoms associated with selenium poisoning.

TL;DR: The tripeptide, reduced glutathione (GSH), is present in high concentration in mammalian red blood cells, where its major role is thought to be the protection of the cell against oxidative damage.