J
Jan S. Moreb
Researcher at University of Florida
Publications - 138
Citations - 5759
Jan S. Moreb is an academic researcher from University of Florida. The author has contributed to research in topics: Transplantation & Multiple myeloma. The author has an hindex of 38, co-authored 134 publications receiving 5197 citations. Previous affiliations of Jan S. Moreb include UF Health Shands Hospital & University of Florida Health.
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Journal ArticleDOI
Lenalidomide after stem-cell transplantation for multiple myeloma
Philip L. McCarthy,Kouros Owzar,Craig C. Hofmeister,David D. Hurd,Hani Hassoun,Paul G. Richardson,Sergio Giralt,Edward A. Stadtmauer,Daniel J. Weisdorf,Ravi Vij,Jan S. Moreb,Natalie S. Callander,Koen van Besien,Teresa Gentile,Luis Isola,Richard T. Maziarz,Don A. Gabriel,Asad Bashey,Heather Landau,Thomas G. Martin,Muzaffar H. Qazilbash,Denise Levitan,Brian McClune,Robert L. Schlossman,Vera Hars,John Postiglione,Chen Jiang,Elizabeth Bennett,Susan Barry,Linda Bressler,Michael Kelly,Michele Seiler,Cara A. Rosenbaum,Parameswaran Hari,Marcelo C. Pasquini,Mary M. Horowitz,Thomas C. Shea,Steven M. Devine,Kenneth C. Anderson,Charles A. Linker +39 more
TL;DR: Lenalidomide maintenance therapy, initiated at day 100 after hematopoietic stem-cell transplantation, was associated with more toxicity and second cancers but a significantly longer time to disease progression and significantly improved overall survival among patients with myeloma.
Journal ArticleDOI
Aldehyde dehydrogenase as a marker for stem cells.
TL;DR: The available tools that can impact ALDH activity and may have the potential to be used therapeutically, specifically targeting the CSC are reviewed and questions that need to be investigated are raised.
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ALDH1A1 and ALDH3A1 expression in lung cancers: correlation with histologic type and potential precursors.
TL;DR: Elevated expression of both enzymes may be associated with malignant transformation to AdenoCA, and cigarette smoking seems to result in increased expression of these enzymes in normal pneumocytes.
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Late onset of invasive aspergillus infection in bone marrow transplant patients at a university hospital.
WB Grow,Jan S. Moreb,D Roque,K Manion,Helen Leather,Vijay Reddy,S.A. Khan,K.J. Finiewicz,H Nguyen,Cornelius J. Clancy,Paulette Mehta,John R. Wingard +11 more
TL;DR: The data illustrate a shift toward a later occurrence of post-transplant IA, suggesting a need for close, prolonged surveillance in the outpatient environment and have important implications in an era of alternate donor transplants and more intense immunosuppression.
Journal ArticleDOI
The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant effects on cell proliferation and drug resistance
Jan S. Moreb,Deniz A. Ucar,Shuhong Han,John K. Amory,Alex S. Goldstein,Blanca Ostmark,Lung-Ji Chang +6 more
TL;DR: The effects of human ALDH isoenzymes, ALDH1A2 and ALDH2, on drug resistance and proliferation, and the specificity of DEAB as an inhibitor are explored, concluding that DEAB is not a specific inhibitor for AL DH1A1 and that Aldefluor assay is not specific for ALDH 1A1 activity.