J
Jane W. Newburger
Researcher at Boston Children's Hospital
Publications - 582
Citations - 64913
Jane W. Newburger is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Kawasaki disease & Medicine. The author has an hindex of 114, co-authored 515 publications receiving 55331 citations. Previous affiliations of Jane W. Newburger include Brigham and Women's Hospital & University of Texas at Austin.
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Journal ArticleDOI
Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association? A Scientific Statement From the American Heart Association
Peter B. Lockhart,Ann F. Bolger,Panos N. Papapanou,Olusegun Osinbowale,Maurizio Trevisan,Matthew E. Levison,Kathryn A. Taubert,Jane W. Newburger,Heather L. Gornik,Michael H. Gewitz,Walter R. Wilson,Sidney C. Smith,Larry M. Baddour +12 more
TL;DR: Whether available data support an independent association between ASVD and PD and whether PD treatment might modify ASVD risks or outcomes is assessed and mechanistic details of both PD and ASVD relevant to this topic are presented.
Journal ArticleDOI
De novo mutations in histone-modifying genes in congenital heart disease
Samir Zaidi,Murim Choi,Hiroko Wakimoto,Lijiang Ma,Jianming Jiang,John D. Overton,Angela Romano-Adesman,Robert D. Bjornson,Roger E. Breitbart,Kerry K. Brown,Nicholas Carriero,Yee Him Cheung,John E. Deanfield,Steve Depalma,Khalid Adnan Mohamed A. Fakhro,Joseph T. Glessner,Hakon Hakonarson,Michael J. Italia,Jonathan R. Kaltman,Juan Pablo Kaski,Richard B. Kim,Jennie Kline,Teresa Lee,Jeremy Leipzig,Alexander Lopez,Shrikant Mane,Laura E. Mitchell,Jane W. Newburger,Michael Parfenov,Itsik Pe'er,George A. Porter,Amy E. Roberts,Ravi Sachidanandam,Stephen Sanders,Howard S. Seiden,Mathew W. State,Sai Lakshmi Subramanian,Irina Tikhonova,Wei Wang,Wei Wang,Dorothy Warburton,Peter White,Ismee A. Williams,Hongyu Zhao,Jonathan G. Seidman,Martina Brueckner,Wendy K. Chung,Bruce D. Gelb,Elizabeth Goldmuntz,Christine E. Seidman,Richard P. Lifton +50 more
TL;DR: Comparing the incidence of de novo mutations in severe CHD cases and controls by analysing exome sequencing of parent–offspring trios suggests that several hundreds of genes collectively contribute to approximately 10% of severeCHD.
Journal ArticleDOI
Comparison of Shunt Types in the Norwood Procedure for Single-Ventricle Lesions
Richard G. Ohye,Lynn A. Sleeper,Lynn Mahony,Jane W. Newburger,Gail D. Pearson,Minmin Lu,Caren S. Goldberg,Sarah Tabbutt,Peter C. Frommelt,Nancy S. Ghanayem,Peter C. Laussen,John F. Rhodes,John F. Rhodes,John F. Rhodes,Alan B. Lewis,Seema Mital,Chitra Ravishankar,Ismee A. Williams,Carolyn Dunbar-Masterson,Andrew M. Atz,Steven D. Colan,L. LuAnn Minich,Christian Pizarro,Kirk R. Kanter,James Jaggers,James Jaggers,James Jaggers,Jeffrey P. Jacobs,Catherine D. Krawczeski,Nancy A. Pike,Brian W. McCrindle,Lisa Virzi,J. William Gaynor +32 more
TL;DR: In children undergoing the Norwood procedure, transplantation-free survival at 12 months was better with the RVPA shunt than with the MBT shunt, and the rate of nonfatal serious adverse events at the age of 12 months were similar in the two groups.
Journal ArticleDOI
Diagnosis and Management of Infective Endocarditis and Its Complications
Arnold S. Bayer,Ann F. Bolger,Kathryn A. Taubert,Walter R. Wilson,James M. Steckelberg,Adolph W. Karchmer,Matthew E. Levison,Henry F. Chambers,Adnan S. Dajani,Michael H. Gewitz,Jane W. Newburger,Michael A. Gerber,Stanford T. Shulman,Thomas J. Pallasch,Tommy W. Gage,Patricia Ferrieri +15 more
TL;DR: The variability in the clinical presentation of IE requires a diagnostic strategy that will be both sensitive for disease detection and specific for its exclusion across all the forms of the disease, and the current literature is reviewed.
Journal ArticleDOI
A Comparison of the Perioperative Neurologic Effects of Hypothermic Circulatory Arrest versus Low-Flow Cardiopulmonary Bypass in Infant Heart Surgery
Jane W. Newburger,Richard A. Jonas,Gil Wernovsky,David Wypij,Paul R. Hickey,Karl C.K. Kuban,David M. Farrell,Gregory L. Holmes,Sandra L. Helmers,Jules Constantinou,Enrique Carrazana,John K. Barlow,Amy Z. Walsh,Kristin C. Lucius,Jane Share,David L. Wessel,Frank L. Hanley,John E. Mayer,Aldo R. Castaneda,James H. Ware +19 more
TL;DR: This randomized, single-center trial compared the incidence of perioperative brain injury after deep hypothermia and support consisting predominantly of total circulatory arrest with the incidence after deep Hypothermic Circulatory arrest in a randomized,single- center trial.