Jean-Jacques Tuech

TL;DR: Assessment of the immune status via Immunoscore provides a potent indicator of tumor recurrence beyond microsatellite-instability staging that could be an important guide for immunotherapy strategies.

TL;DR: It is confirmed that KRAS mutation is highly predictive of a non-response to cetuximab plus chemotherapy in MCRC and highlights the need to use sensitive molecular methods, such as SNaPshot or PCR-LCR assays, to ensure an efficient mutation detection.

TL;DR: Waiting 11 weeks after RCT did not increase the rate of pCR after surgical resection, and a longer waiting period may be associated with higher morbidity and more difficult surgical resections.

TL;DR: A prospective, randomised, open-label, multicentre, phase 3 trial at 15 tertiary centres in France that were experts in the treatment of rectal cancer failed to show superiority of local excision over total mesorectal excision in patients with a good response after chemoradiotherapy.

TL;DR: The CPGs for peritonitis are based on a consensus between the various disciplines involved in the management of these patients concerning a number of themes such as: diagnostic strategy and the place of imaging; time to management; the Place of microbiological specimens; targets of empirical anti-infective therapy; duration of anti- Infective therapy.