A
Anne Berger
Researcher at University of Paris
Publications - 124
Citations - 13191
Anne Berger is an academic researcher from University of Paris. The author has contributed to research in topics: Internal medicine & Cancer. The author has an hindex of 35, co-authored 105 publications receiving 10034 citations.
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Journal ArticleDOI
Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.
Gabriela Bindea,Bernhard Mlecnik,Bernhard Mlecnik,Bernhard Mlecnik,Marie Tosolini,Marie Tosolini,Marie Tosolini,Amos Kirilovsky,Amos Kirilovsky,Amos Kirilovsky,Maximilian J. Waldner,Anna C. Obenauf,Helen K. Angell,Helen K. Angell,Helen K. Angell,Tessa Fredriksen,Tessa Fredriksen,Tessa Fredriksen,Lucie Lafontaine,Lucie Lafontaine,Lucie Lafontaine,Anne Berger,Patrick Bruneval,Wolf H. Fridman,Wolf H. Fridman,Wolf H. Fridman,Christoph Becker,Franck Pagès,Michael R. Speicher,Zlatko Trajanoski,Jérôme Galon +30 more
TL;DR: The immune landscape in human colorectal cancer is revealed and the major hallmarks of the microenvironment associated with tumor progression and recurrence are revealed.
Journal ArticleDOI
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
Franck Pagès,Bernhard Mlecnik,Florence Marliot,Gabriela Bindea,Gabriela Bindea,Gabriela Bindea,Fang Shu Ou,Carlo Bifulco,Alessandro Lugli,Inti Zlobec,Tilman T. Rau,Martin D. Berger,Iris D. Nagtegaal,Elisa Vink-Börger,Arndt Hartmann,Carol Geppert,Julie Kolwelter,Susanne Merkel,Robert Grützmann,Marc Van den Eynde,Anne Jouret-Mourin,Alex Kartheuser,Daniel Léonard,Christophe Remue,Julia Y. Wang,Julia Y. Wang,Prashant Bavi,Michael H.A. Roehrl,Michael H.A. Roehrl,Michael H.A. Roehrl,Pamela S. Ohashi,Linh T. Nguyen,Seong Jun Han,Heather L. MacGregor,Sara Hafezi-Bakhtiari,Bradly G. Wouters,Giuseppe Masucci,Emilia Andersson,Eva Zavadova,Michal Vocka,Jan Spacek,Lubos Petruzelka,Bohuslav Konopasek,Pavel Dundr,Helena Skalova,Kristyna Nemejcova,Gerardo Botti,Fabiana Tatangelo,Paolo Delrio,Gennaro Ciliberto,Michele Maio,Luigi Laghi,Fabio Grizzi,Tessa Fredriksen,Tessa Fredriksen,Tessa Fredriksen,Bénédicte Buttard,Bénédicte Buttard,Bénédicte Buttard,Mihaela Angelova,Mihaela Angelova,Mihaela Angelova,Angela Vasaturo,Angela Vasaturo,Angela Vasaturo,Pauline Maby,Pauline Maby,Pauline Maby,Sarah E. Church,Helen K. Angell,Lucie Lafontaine,Lucie Lafontaine,Lucie Lafontaine,Daniela Bruni,Daniela Bruni,Daniela Bruni,Carine El Sissy,Nacilla Haicheur,Amos Kirilovsky,Anne Berger,Christine Lagorce,Jeffrey P. Meyers,Christopher Paustian,Zipei Feng,Carmen Ballesteros-Merino,Jeroen R. Dijkstra,Carlijn van de Water,Shannon van Vliet,Nikki Knijn,Ana Maria Mușină,Dragos Viorel Scripcariu,Boryana Popivanova,Mingli Xu,Tomonobu Fujita,Shoichi Hazama,Nobuaki Suzuki,Hiroaki Nagano,Kiyotaka Okuno,Toshihiko Torigoe,Noriyuki Sato,Tomohisa Furuhata,Ichiro Takemasa,Kyogo Itoh,P. Patel,Hemangini H. Vora,Birva Shah,Jayendrakumar B. Patel,Kruti N. Rajvik,Shashank J. Pandya,Shilin N. Shukla,Yili Wang,Guanjun Zhang,Yutaka Kawakami,Francesco M. Marincola,Paolo A. Ascierto,Daniel J. Sargent,Bernard A. Fox,Bernard A. Fox,Jérôme Galon,Jérôme Galon,Jérôme Galon +120 more
TL;DR: The immunoscore provides a reliable estimate of the risk of recurrence in patients with colon cancer and supports the implementation of the consensus Immunoscore as a new component of a TNM-Immune classification of cancer.
Journal ArticleDOI
Towards the introduction of the 'Immunoscore' in the classification of malignant tumours.
Jérôme Galon,Jérôme Galon,Jérôme Galon,Bernhard Mlecnik,Bernhard Mlecnik,Bernhard Mlecnik,Gabriela Bindea,Gabriela Bindea,Gabriela Bindea,Helen K. Angell,Helen K. Angell,Helen K. Angell,Anne Berger,Christine Lagorce,Alessandro Lugli,Inti Zlobec,Arndt Hartmann,Carlo Bifulco,Iris D. Nagtegaal,Richard Palmqvist,Giuseppe Masucci,Gerardo Botti,Fabiana Tatangelo,Paolo Delrio,Michele Maio,Luigi Laghi,Fabio Grizzi,Martin Asslaber,Corrado D'Arrigo,Fernando Vidal-Vanaclocha,Eva Zavadova,Lotfi Chouchane,Pamela S. Ohashi,Sara Hafezi-Bakhtiari,Bradly G. Wouters,Michael H.A. Roehrl,Linh V. Nguyen,Yutaka Kawakami,Shoichi Hazama,Kiyotaka Okuno,Shuji Ogino,Peter Gibbs,Paul Waring,Noriyuki Sato,Toshihiko Torigoe,Kyogo Itoh,P. Patel,Shilin N. Shukla,Yili Wang,Scott Kopetz,Frank A. Sinicrope,Viorel Scripcariu,Paolo A. Ascierto,Francesco M. Marincola,Bernard A. Fox,Bernard A. Fox,Franck Pagès +56 more
TL;DR: In colorectal cancer, the Immunoscore may add to the significance of the current AJCC/UICC TNM classification, since it has been demonstrated to be a prognostic factor superior to the AJCC or UICCTNM classification.
Journal ArticleDOI
Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value
Laetitia Marisa,Aurélien de Reyniès,Alex Duval,Alex Duval,Janick Selves,Marie Pierre Gaub,Laure Vescovo,Marie-Christine Etienne-Grimaldi,Renaud Schiappa,Dominique Guenot,Mira Ayadi,Sylvain Kirzin,Maurice Chazal,Jean-François Fléjou,Jean-François Fléjou,Daniel Benchimol,Anne Berger,Arnaud Lagarde,Erwan Pencreach,F. Piard,Dominique Elias,Yann Parc,Sylviane Olschwang,Gérard Milano,Pierre Laurent-Puig,Valérie Boige,Valérie Boige +26 more
TL;DR: A new classification of CC into six molecular subtypes that arise through distinct biological pathways that improves the current disease stratification based on clinicopathological variables and common DNA markers is described.
Journal ArticleDOI
Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer
Marie Tosolini,Amos Kirilovsky,Bernhard Mlecnik,Tessa Fredriksen,Stéphanie Mauger,Gabriela Bindea,Anne Berger,Patrick Bruneval,Wolf H. Fridman,Franck Pagès,Jérôme Galon +10 more
TL;DR: It is argued that functional Th1 and Th17 clusters yield opposite effects on patient survival in colorectal cancer, and they provide complementary information that may improve prognosis.