J
Jennifer Pasquier
Researcher at Cornell University
Publications - 52
Citations - 2007
Jennifer Pasquier is an academic researcher from Cornell University. The author has contributed to research in topics: Tumor microenvironment & Ovarian cancer. The author has an hindex of 22, co-authored 47 publications receiving 1555 citations. Previous affiliations of Jennifer Pasquier include University of Paris & Hamad Medical Corporation.
Papers
More filters
Journal ArticleDOI
Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance
Jennifer Pasquier,Bella S. Guerrouahen,Hamda Al. Thawadi,Pegah Ghiabi,Mahtab Maleki,Nadine Abu-Kaoud,Arthur Jacob,Massoud Mirshahi,Ludovic Galas,Shahin Rafii,Frank Le Foll,Arash Rafii +11 more
TL;DR: The results illustrate the perfusion-independent role of the endothelium by showing a direct endothelial to cancer cell mitochondrial exchange associated to phenotypic modulation, which supports another role in the constitution of the metastatic niche.
Journal ArticleDOI
Halfway between 2D and Animal Models: Are 3D Cultures the Ideal Tool to Study Cancer-Microenvironment Interactions?
TL;DR: A comprehensive review of the different 3D methods developed recently is presented, and the pros and cons of 3D culture compared to 2D when studying interactions between cancer cells and their microenvironment are discussed.
Journal ArticleDOI
Tunneling Nanotubes and Gap Junctions-Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions.
Jennifer L. Ariazi,Andrew B. Benowitz,Vern de Biasi,Monique L. den Boer,Stephanie Cherqui,Haifeng Cui,Nathalie Douillet,Eliseo A. Eugenin,Eliseo A. Eugenin,David Favre,Spencer Goodman,Karine Gousset,Dorit Hanein,David I. Israel,Shunsuke Kimura,Robert B. Kirkpatrick,Nastaran Z. Kuhn,Claire G. Jeong,Emil Lou,Robbie B. Mailliard,Stephen Maio,George Okafo,Matthias Osswald,Matthias Osswald,Jennifer Pasquier,Roel Polak,Gabriele Pradel,Bob de Rooij,Peter Schaeffer,Vytenis Arvydas Skeberdis,Ian F. Smith,Ahmad Tanveer,Niels Volkmann,Zhenhua Wu,Chiara Zurzolo +34 more
TL;DR: The combined data from numerous laboratories indicate that some TNT mediate a long-range gap junctional communication to coordinate metabolism and signaling, in relation to infectious, genetic, metabolic, cancer, and age-related diseases.
Journal ArticleDOI
Different Modalities of Intercellular Membrane Exchanges Mediate Cell-to-cell P-glycoprotein Transfers in MCF-7 Breast Cancer Cells
Jennifer Pasquier,Jennifer Pasquier,Ludovic Galas,Céline Boulangé-Lecomte,Damien Rioult,Florence Bultelle,Pierre Magal,Glenn F. Webb,Frank Le Foll +8 more
TL;DR: It is shown that intercellular transfers of functional P-gp occur by two different but complementary modalities through donor-recipient cells interactions in the absence of drug selection pressure, indicating that new treatment strategies designed to overcome MDR may include inhibition of both microparticles and Tunneling nanotube-mediated inter cellular P- gp transfers.
Journal ArticleDOI
Epithelial to Mesenchymal Transition in a Clinical Perspective.
TL;DR: The attempts made to block EMT in the therapeutic context are summarized and analyzed and the limitations of EMT targeting such tumor heterogeneity or the dynamics of E MT during disease progression are pointed out.