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Vern de Biasi

Researcher at GlaxoSmithKline

Publications -  8
Citations -  399

Vern de Biasi is an academic researcher from GlaxoSmithKline. The author has contributed to research in topics: Capillary electrophoresis & Molecularly imprinted polymer. The author has an hindex of 7, co-authored 8 publications receiving 352 citations.

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Tunneling Nanotubes and Gap Junctions-Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions.

TL;DR: The combined data from numerous laboratories indicate that some TNT mediate a long-range gap junctional communication to coordinate metabolism and signaling, in relation to infectious, genetic, metabolic, cancer, and age-related diseases.
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Approaches to the rational design of molecularly imprinted polymers

TL;DR: A multi-analyte competition rebind assay was developed to select suitable sulfonamides to be used as the template for the MIP, and for the rebind analyte in the chemometric optimisation study, to avoid the inaccuracies in measurement caused by template bleed.
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Chiral separation of basic drugs by capillary electrophoresis with carboxymethylcyclodextrins.

TL;DR: Capillary electrophoresis with carboxymethylated beta- or gamma-cyclodextrins was used to achieve the rapid enantiomeric separation of a set of basic drugs and it was shown that the solute affinity for the chiral selector is not related to its enantioresolution factor.
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The analysis of basic and acidic compounds using non-aqueous CE and non-aqueous CE-MS.

TL;DR: It has been shown that non-aqueous capillary electrophoresis (NACE) can provide improved separations in comparison to those obtained using conventional CE under aqueous conditions (ACE).
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Chiral HPLC method for chiral purity determination of paroxetine drug substance.

TL;DR: The method development was performed to establish a suitable HPLC system in order to separate both enantiomers and it was found that a system based on a Chiralpak AD column was suitable for the analysis.