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José Almeida Cruz

Researcher at University of Strasbourg

Publications -  9
Citations -  1309

José Almeida Cruz is an academic researcher from University of Strasbourg. The author has contributed to research in topics: RNA & Gene. The author has an hindex of 9, co-authored 9 publications receiving 1145 citations. Previous affiliations of José Almeida Cruz include Champalimaud Foundation & Centre national de la recherche scientifique.

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The dynamic landscapes of RNA architecture.

TL;DR: A wealth of information has emerged from analyses of structures and from the use of innovative biophysical tools, and such efforts are opening new vistas on the RNA folding landscape.
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RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures

TL;DR: This paper is a report of a second round of RNA-Puzzles, a collective and blind experiment in three-dimensional (3D) RNA structure prediction, where seven groups predicted a lariat-capping ribozyme, as well as riboswitches complexed to adenosylcobalamin and tRNA, using state-of-the-art methods.
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New metrics for comparing and assessing discrepancies between RNA 3D structures and models.

TL;DR: The results show that there is little correlation between RMSD and interaction network fidelity, and the deformation profile is a tool that allows for rapid assessment of the origins of discrepancies.