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Josée Dostie

Researcher at McGill University

Publications -  74
Citations -  12153

Josée Dostie is an academic researcher from McGill University. The author has contributed to research in topics: Chromatin & Chromosome conformation capture. The author has an hindex of 42, co-authored 70 publications receiving 10960 citations. Previous affiliations of Josée Dostie include University of Massachusetts Medical School & University of Pennsylvania.

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The ENCODE (ENCyclopedia of DNA elements) Project

Elise A. Feingold, +196 more
- 22 Oct 2004 - 
TL;DR: The ENCyclopedia Of DNA Elements (ENCODE) Project is organized as an international consortium of computational and laboratory-based scientists working to develop and apply high-throughput approaches for detecting all sequence elements that confer biological function.
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miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

TL;DR: This work reports that Gemin3 and Gemin4 are also in a separate complex that contains eIF2C2, a member of the Argonaute protein family, which is a large approximately 15S RNP that contains numerous microRNAs (miRNAs).
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Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements

TL;DR: A high-throughput 3C approach, 3C-Carbon Copy (5C), that employs microarrays or quantitative DNA sequencing using 454-technology as detection methods that should be widely applicable for large-scale mapping of cis- and trans- interaction networks of genomic elements and for the study of higher-order chromosome structure.
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Complex multi-enhancer contacts captured by genome architecture mapping

TL;DR: A genome-wide method for measuring chromatin contacts and other features of three-dimensional chromatin topology on the basis of sequencing DNA from a large collection of thin nuclear sections is reported, highlighting a role for gene-expression-specific contacts in organizing the genome in mammalian nuclei.
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Complexity of chromatin folding is captured by the strings and binders switch model

TL;DR: The strings and binders switch model reproduces the recently proposed “fractal–globule” model, but only as one of many possible transient conformations.