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Josef Jampilek

Researcher at Comenius University in Bratislava

Publications -  331
Citations -  6091

Josef Jampilek is an academic researcher from Comenius University in Bratislava. The author has contributed to research in topics: Lipophilicity & Chemistry. The author has an hindex of 36, co-authored 303 publications receiving 4695 citations. Previous affiliations of Josef Jampilek include Palacký University, Olomouc & Slovak Academy of Sciences.

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Journal ArticleDOI

Activity of ring-substituted 8-hydroxyquinoline-2-carboxanilides against intestinal sulfate-reducing bacteria Desulfovibrio piger

TL;DR: The antibacterial efficacy of the most active C’(3)-substituted compounds practically did not change with increasing compound lipophilicity, indicating that this position of substitution is favorable for significant antimicrobial effect.
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Investigation of new acyloxy derivatives of cholic acid and their esters as drug absorption modifiers.

TL;DR: Most of the target compounds showed minimal anti-proliferative activity (IC(50)>37 μM), indicating they would have low cytotoxicity when administered as chemical absorption modifiers.
Journal ArticleDOI

Ring-substituted 8-hydroxyquinoline-2-carboxanilides as potential antimycobacterial agents.

TL;DR: In this study, a series of twenty-two ring-substituted 8-hydroxyquinoline-2-carboxanilides was prepared and characterized and some of the tested compounds showed the antimycobacterial activity against M. paratuberculosis comparable with or higher than that of rifampicin.
Journal ArticleDOI

Sulfolane: Magic Extractor or Bad Actor? Pilot-Scale Study on Solvent Corrosion Potential

TL;DR: In this paper, a comprehensive review focusing mainly on the state-of-the-art aspects of the sulfolane synthesis, application of sulfolanes as an extractive solvent due to its unique physicochemical properties as well as the potential of sulfolsane to cause equipment corrosion and subsequent spills is presented.
Book ChapterDOI

Application of Nanobioformulations for Controlled Release and Targeted Biodistribution of Drugs

TL;DR: In this paper, the authors focus on natural-based biocompatible and biodegradable materials that are used as matrices/carriers for controlled release or targeted biodistribution of nanoscale active pharmaceutical ingredients with low toxicity and favorable pharmacokinetics.