J
Joseph A. Church
Researcher at University of Southern California
Publications - 240
Citations - 8097
Joseph A. Church is an academic researcher from University of Southern California. The author has contributed to research in topics: Virus & Antibody. The author has an hindex of 43, co-authored 236 publications receiving 7452 citations. Previous affiliations of Joseph A. Church include Boston Children's Hospital & Children's Hospital Los Angeles.
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Journal ArticleDOI
Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen
TL;DR: The extraordinary dependence of HIV on human host proteins for efficient transmission and replication provides many new potential targets for antiretroviral therapy.
Journal ArticleDOI
Newborn Screening for Severe Combined Immunodeficiency in 11 Screening Programs in the United States
Antonia Kwan,Roshini S. Abraham,Robert Currier,Amy Brower,Karen Andruszewski,Jordan K. Abbott,Mei W. Baker,Mark Ballow,Louis Bartoshesky,Francisco A. Bonilla,Charles D. Brokopp,Edward G. Brooks,Michele Caggana,Jocelyn Celestin,Joseph A. Church,Anne Marie Comeau,James A. Connelly,Morton J. Cowan,Charlotte Cunningham-Rundles,Trivikram Dasu,Nina Dave,Maria Teresa de la Morena,Ulrich A. Duffner,Chin-To Fong,Lisa R. Forbes,Lisa R. Forbes,Debra Freedenberg,Erwin W. Gelfand,Jaime E. Hale,I. Celine Hanson,I. Celine Hanson,Beverly N. Hay,Diana Hu,Anthony J. Infante,Daisy Johnson,Neena Kapoor,Denise M. Kay,Donald B. Kohn,Rachel Lee,Heather K. Lehman,Zhili Lin,Fred Lorey,Aly Abdel-Mageed,Adrienne Manning,Sean A. McGhee,Sean A. McGhee,Theodore B. Moore,Stanley J. Naides,Luigi D. Notarangelo,Jordan S. Orange,Jordan S. Orange,Sung-Yun Pai,Matthew H. Porteus,Matthew H. Porteus,Ray Rodriguez,Neil Romberg,John M. Routes,Mary Ruehle,Arye Rubenstein,Carlos A. Saavedra-Matiz,Ginger Scott,Patricia M. Scott,Elizabeth Secord,Christine M. Seroogy,William T. Shearer,William T. Shearer,Subhadra Siegel,Stacy K. Silvers,E. Richard Stiehm,Robert W. Sugerman,John L. Sullivan,Susan Tanksley,Millard L. Tierce,James W. Verbsky,Beth Vogel,Rosalyn Walker,Kelly Walkovich,Jolan E. Walter,Richard L. Wasserman,Michael S. Watson,Geoffrey A. Weinberg,Leonard B. Weiner,Heather Wood,Anne B. Yates,Jennifer M. Puck +84 more
TL;DR: Newborn screening in 11 programs in the United States identified SCID in 1 in 58,000 infants, with high survival, and the usefulness of detection of non-SCID T-cell lymphopenia by the same screening remains to be determined.
Journal ArticleDOI
Safety and antiretroviral activity of chronic subcutaneous administration of t-20 in human immunodeficiency virus 1-infected children
TL;DR: The use of combination antiretroviral therapy has been associated with a substantial decline in morbidity and mortality in human immunodeficiency virus (HIV)-infected individuals and pharmacologic agents effective at alternative stages in the replication cycle of the virus are identified.
Journal ArticleDOI
Massive Infection and Loss of Memory CD4+ T Cells in Multiple Tissues During Acute SIV Infection
TL;DR: This study demonstrated that in this monkey model, memory CD4+ T cells are depleted in multiple tissues during acute SIV infection, and it is strongly suggested that this loss, at least in adult animals and humans, is irreversible.
Journal ArticleDOI
Case report: evidence for transplacental transfer of maternally administered infliximab to the newborn.
Eric A. Vasiliauskas,Eric A. Vasiliauskas,Joseph A. Church,Neil S. Silverman,Mary J. Barry,Stephan R. Targan,Stephan R. Targan,Marla Dubinsky,Marla Dubinsky +8 more
TL;DR: Clinically significant infliximab levels were detected in the offspring and the timing of infusions to minimize antibody transfer to the fetus might be an important strategic consideration when therapeutic antibodies are used in pregnancy.