E
Eric A. Vasiliauskas
Researcher at Cedars-Sinai Medical Center
Publications - 166
Citations - 9089
Eric A. Vasiliauskas is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Inflammatory bowel disease & Crohn's disease. The author has an hindex of 44, co-authored 153 publications receiving 8611 citations. Previous affiliations of Eric A. Vasiliauskas include University of Groningen & University of California, Los Angeles.
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Journal ArticleDOI
Genome-wide association identifies multiple ulcerative colitis susceptibility loci
Dermot P.B. McGovern,Agnes Gardet,Leif Törkvist,Philippe Goyette,Jonah Essers,Kent D. Taylor,Benjamin M. Neale,Rick Twee-Hee Ong,Caroline Lagacé,Chun Li,Todd Green,Christine Stevens,Claudine Beauchamp,Phillip Fleshner,Marie Carlson,Mauro D'Amato,Jonas Halfvarson,Martin L. Hibberd,Mikael Lördal,Leonid Padyukov,Angelo Andriulli,Elisabetta Colombo,Anna Latiano,Orazio Palmieri,Edmond Jean Bernard,Colette Deslandres,Daan W. Hommes,Dirk J. de Jong,Pieter C. F. Stokkers,Rinse K. Weersma,Yashoda Sharma,Mark S. Silverberg,Judy H. Cho,Jing Wu,Jing Wu,Kathryn Roeder,Steven R. Brant,L Phillip Schumm,Richard H. Duerr,Marla Dubinsky,Nicole L. Glazer,Talin Haritunians,Andrew Ippoliti,Gil Y. Melmed,David S. Siscovick,Eric A. Vasiliauskas,Stephan R. Targan,Vito Annese,Cisca Wijmenga,Sven Pettersson,Jerome I. Rotter,Jerome I. Rotter,Ramnik J. Xavier,Mark J. Daly,John D. Rioux,Mark Seielstad +55 more
TL;DR: Two distinct genome-wide association studies of ulcerative colitis are presented and their joint analysis with a previously published scan shows that roughly half of the known Crohn's disease associations are shared with ulceratives colitis, thereby providing insight into disease pathogenesis.
Journal ArticleDOI
Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease
William S Mow,Eric A. Vasiliauskas,Ying Chao Lin,Phillip Fleshner,Konstantinos A. Papadakis,Kent D. Taylor,Carol J. Landers,Maria T. Abreu-Martin,Jerome I. Rotter,Huiying Yang,Stephan R. Targan +10 more
TL;DR: I2 and anti-Escherichia coli outer membrane porin C are associated with Crohn's disease phenotypes, and patients with the highest level of serum reactivity toward an increasing number of microbiota have the greatest frequency of strictures, internal perforations, and small bowel surgery.
Journal ArticleDOI
Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease.
Stephan R. Targan,Carol J. Landers,Huiying Yang,Michael J. Lodes,Michael J. Lodes,Yingzi Cong,Yingzi Cong,Konstantinos A. Papadakis,Eric A. Vasiliauskas,Charles O. Elson,Charles O. Elson,Robert M. Hershberg,Robert M. Hershberg +12 more
TL;DR: Serum responses to CBir1 independently identify a unique subset of patients with complicated CD patients, and this bacterial antigen was identified in a murine model and has a similar pattern of aberrant reactivity in a subset of CD patients.
Journal ArticleDOI
Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
Dermot P.B. McGovern,Matthew Jones,Kent D. Taylor,Kristin D. Marciante,Xiaofei Yan,Marla Dubinsky,Andrew Ippoliti,Eric A. Vasiliauskas,Dror Berel,Carrie Derkowski,Deb Dutridge,Phil Fleshner,David Q. Shih,Gil Y. Melmed,Emebet Mengesha,Lily King,Sheila Pressman,Talin Haritunians,Xiuqing Guo,Stephan R. Targan,Jerome I. Rotter +20 more
TL;DR: In this paper, the authors performed a genome-wide association study (GWAS) in 896 Crohn's disease (CD) cases and 3204 healthy controls all of Caucasian origin as defined by multidimensional scaling.
Journal ArticleDOI
Patients with inflammatory bowel disease are at risk for vaccine-preventable illnesses.
Gil Y. Melmed,Andrew Ippoliti,Konstantinos A. Papadakis,Tram T. Tran,Jaime L Birt,Susie K. Lee,Robert W. Frenck,Stephan R. Targan,Eric A. Vasiliauskas +8 more
TL;DR: Immunization against selected vaccine-preventable illnesses was uncommon in patients with IBD, despite the presence of significant risk factors.