J
Joseph M. Pilewski
Researcher at University of Pittsburgh
Publications - 322
Citations - 17263
Joseph M. Pilewski is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Lung transplantation & Cystic fibrosis. The author has an hindex of 65, co-authored 285 publications receiving 15142 citations. Previous affiliations of Joseph M. Pilewski include Boston Children's Hospital & University of Pennsylvania.
Papers
More filters
Journal ArticleDOI
WS7.3 VX-661, an investigational CFTR corrector, in combination with ivacaftor, a CFTR potentiator, in patients with CF and homozygous for the F508Del-CFTR mutation: Interim analysis
Journal ArticleDOI
A polymorphism linked to elevated levels of interferon-γ is associated with an increased risk of cytomegalovirus disease among Caucasian lung transplant recipients at a single center.
Dimitra Mitsani,M. Hong Nguyen,Diana M. Girnita,Kathleen Spichty,Eun J. Kwak,Fernanda P. Silveira,Yoshiya Toyoda,Joseph M. Pilewski,Maria Crespo,Jay K. Bhama,Rima Abdel-Massih,Diana Zaldonis,Adriana Zeevi,Cornelius J. Clancy +13 more
TL;DR: A genetic predisposition to elevated IFN-γ levels may play a dual role in controlling active CMV infection among lung transplant recipients receiving alemtuzumab induction and valganciclovir prophylaxis, limiting the extent of viral replication in serum but increasing the risk of CMV disease.
Journal ArticleDOI
Gastrin-releasing peptide receptor expression in non-cancerous bronchial epithelia is associated with lung cancer: a case-control study
Ann Marie Egloff,Autumn Gaither Davis,Yongli Shuai,Stephanie R. Land,Joseph M. Pilewski,James D. Luketich,Rodney J. Landreneau,York E. Miller,Jennifer R. Grandis,Jill M. Siegfried +9 more
TL;DR: Bronchial GRPR expression in non-cancerous bronchial epithelium was significantly associated with the presence of lung cancer in never and former smokers and the association in males and females was found.
Journal ArticleDOI
Impact of Graft Volume Reduction for Oversized Grafts After Lung Transplantation on Outcome in Recipients With End-stage Restrictive Pulmonary Diseases
Norihisa Shigemura,Christian Bermudez,Brack G. Hattler,Bruce E. Johnson,Maria Crespo,Joseph M. Pilewski,Yoshiya Toyoda +6 more
TL;DR: An oversized graft may lead to a higher incidence of short-term clinical complications with reduced pulmonary function improvement post-operatively in lung transplantation recipients with end-stage restrictive pulmonary diseases.
Journal ArticleDOI
Lung Transplantation for Patients With High Lung Allocation Score: Single-Center Experience
T. Horai,Norihisa Shigemura,Cynthia J. Gries,Joseph M. Pilewski,Jay K. Bhama,Christian Bermudez,Diana Zaldonis,Yoshiya Toyoda +7 more
TL;DR: Lung transplant in patients with high a LAS is associated with significantly decreased survival and increased complications compared with patients with a low LAS, and ischemic time greater than 8 hours is a significant predictor of death in patientswith a high LAS.