J
Joseph M. Pilewski
Researcher at University of Pittsburgh
Publications - 322
Citations - 17263
Joseph M. Pilewski is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Lung transplantation & Cystic fibrosis. The author has an hindex of 65, co-authored 285 publications receiving 15142 citations. Previous affiliations of Joseph M. Pilewski include Boston Children's Hospital & University of Pennsylvania.
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Journal ArticleDOI
Symptom Burden and Unmet Existential Needs in Adults With Cystic Fibrosis.
Elizabeth T. Trandel,Joseph M. Pilewski,Elisabeth P. Dellon,Laura T Moreines,Jonathan G. Yabes,Kwonho Jeong,Robert M. Arnold,Dio Kavalieratos +7 more
TL;DR: For each six-point increase in burden, there was an increased odds of reporting need for support with learning to feel in control, feelings about death and dying, fears about CF worsening, uncertainty about the future, and concerns about worries of others.
Journal ArticleDOI
WS01.4 VX-661 in combination with ivacaftor in patients with cystic fibrosis and the F508del-CFTR mutation
TL;DR: The data show that the VX-661/IVA combination may benefit patients with CF who are homozygous for F508del and may enhance the benefit of IVA in CF patients with F508Del/G551D.
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Elexacaftor-Tezacaftor- Ivacaftor improves sinonasal outcomes in cystic fibrosis.
Amanda L. Stapleton,Adam J. Kimple,Jennifer L. Goralski,Seyed Mehdi Nouraie,Barton F. Branstetter,Amber D. Shaffer,Joseph M. Pilewski,Brent A. Senior,Stella E. Lee,Anna C. Zemke +9 more
TL;DR: In this paper , the authors tested the hypothesis that ELX/TEZ/IVA improves sinonasal disease in CF using a pre/post, observational cohort study conducted at two sites.
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Modulation of tissue resident memory T cells by glucocorticoids after acute cellular rejection in lung transplantation
Mark E. Snyder,Kaveh Moghbeli,Anna Bondonese,Andrew Craig,Iulia Popescu,Li Fan,Tracy Tabib,Robert Lafyatis,Kong-sai Chen,Humberto E. Trejo Bittar,Elizabeth A. Lendermon,Joseph M. Pilewski,Bruce E. Johnson,Silpa Kilaru,Yingze Zhang,Pablo G. Sanchez,Jonathan K. Alder,Peter J. Sims,John F. McDyer +18 more
TL;DR: During acute cellular rejection after lung transplantation, there is an intra-allograft oligoclonal expansion of cytotoxic CD8+ T cells, and expanded T cell clones persist as transcriptionally reprogrammed, airway-centric tissue resident memory T cells.
Journal ArticleDOI
Prevalence of unmet palliative care needs in adults with cystic fibrosis.
Elizabeth T. Trandel,Joseph M. Pilewski,Elisabeth P. Dellon,Kwonho Jeong,Jonathan G. Yabes,Laura T Moreines,Robert M. Arnold,Zachariah Hoydich,Dio Kavalieratos +8 more
TL;DR: Routine screening of unmet PC needs, using tools such as the SCNS-34, may enable CF care teams to optimize the provision of primary and specialist PC.