J
Joseph M. Pilewski
Researcher at University of Pittsburgh
Publications - 322
Citations - 17263
Joseph M. Pilewski is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Lung transplantation & Cystic fibrosis. The author has an hindex of 65, co-authored 285 publications receiving 15142 citations. Previous affiliations of Joseph M. Pilewski include Boston Children's Hospital & University of Pennsylvania.
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Journal ArticleDOI
Rescue alemtuzumab for refractory acute cellular rejection and bronchiolitis obliterans syndrome after lung transplantation
Christopher R. Ensor,Lindsey C. Rihtarchik,Matthew R. Morrell,J.W. Awori Hayanga,Alicia B. Lichvar,Joseph M. Pilewski,Stephen R. Wisniewski,B.A. Johnson,Jonathan D'Cunha,Adriana Zeevi,John F. McDyer +10 more
TL;DR: RacR patients with BOS 1 may have transient benefit, and patients with advanced BOS seem not to respond to alemtuzumab appears useful for rACR, according to a report on the largest cohort of lung transplant recipients treated with rescue alemtsuumab for rACP or BOS.
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Atrial arrhythmias after lung transplantation: Incidence and risk factors in 652 lung transplant recipients
Alex M. D'Angelo,Ernest G. Chan,J.W. Awori Hayanga,David D. Odell,Joseph M. Pilewski,Maria Crespo,Matthew R. Morrell,Norihisa Shigemura,James D. Luketich,Christian Bermudez,Andrew D. Althouse,Jonathan D'Cunha +11 more
TL;DR: Increasing age and before coronary artery bypass grafting were identified as independent risk factors for AA development and better understanding of these risk factors may improve identification of patients at heightened risk after transplantation.
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Gene therapy for airway diseases: continued progress toward identifying and overcoming barriers to efficiency.
TL;DR: Efforts to understand the barriers to gene transfer have successfully identified a series of epithelial cell defenses against viral infection and large molecule delivery to the nucleus, which may provide lessons that will be applicable to other target cells in the lung.
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Adenovirus-mediated gene transfer to human bronchial submucosal glands using xenografts.
Joseph M. Pilewski,John F. Engelhardt,Joseph E. Bavaria,Larry R. Kaiser,James M. Wilson,Steven M. Albelda +5 more
TL;DR: In this article, an in vivo model was developed by heterotopically transplanting human bronchial segments from both normal and CF lung tissue into severe combined immunodeficient mice.
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Absorptive clearance of DTPA as an aerosol-based biomarker in the cystic fibrosis airway
Timothy E. Corcoran,Kristina Thomas,Michael M. Myerburg,Ashok Muthukrishnan,Lawrence Weber,Raymond A. Frizzell,Joseph M. Pilewski +6 more
TL;DR: A study was performed to determine whether the absorption of a small radiolabelled hydrophilic molecule (Indium-111 (In-)DTPA) would be increased in CF airways and the absorptive component of In-DTPA clearance was increased in the airway-dominated central lung zones in CF.