J
Julian Buchrieser
Researcher at Pasteur Institute
Publications - 35
Citations - 2652
Julian Buchrieser is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Antibody & Medicine. The author has an hindex of 13, co-authored 29 publications receiving 1229 citations. Previous affiliations of Julian Buchrieser include University of Oxford & Centre national de la recherche scientifique.
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Journal ArticleDOI
Sensitivity of infectious SARS-CoV-2 B.1.1.7 and B.1.351 variants to neutralizing antibodies.
Delphine Planas,Delphine Planas,Timothée Bruel,Timothée Bruel,Ludivine Grzelak,Florence Guivel-Benhassine,Florence Guivel-Benhassine,Isabelle Staropoli,Isabelle Staropoli,Françoise Porrot,Françoise Porrot,Cyril Planchais,Julian Buchrieser,Julian Buchrieser,Maaran Michael Rajah,Elodie Bishop,Mélanie Albert,Mélanie Albert,Flora Donati,Flora Donati,Matthieu Prot,Sylvie Behillil,Sylvie Behillil,Vincent Enouf,Vincent Enouf,Marianne Maquart,Mounira Smati-Lafarge,Emmanuelle Varon,Frédérique Schortgen,Layla Yahyaoui,María González,Jérôme De Seze,Hélène Péré,David Veyer,Aymeric Sève,Etienne Simon-Loriere,Samira Fafi-Kremer,Karl Stefic,Hugo Mouquet,Laurent Hocqueloux,Sylvie van der Werf,Sylvie van der Werf,Thierry Prazuck,Olivier Schwartz,Olivier Schwartz +44 more
TL;DR: In this paper, the sensitivity of the two variants to SARS-CoV-2 antibodies present in sera and nasal swabs from individuals infected with previously circulating strains or who were recently vaccinated, in comparison with a D614G reference virus was examined.
Journal ArticleDOI
A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response
Walther Haenseler,Stephen N. Sansom,Julian Buchrieser,Sarah E. Newey,Craig S. Moore,Francesca J. Nicholls,Satyan Chintawar,Christian Schnell,Jack P. Antel,Nicholas D. Allen,M Z Cader,Richard Wade-Martins,William James,Sally A. Cowley +13 more
TL;DR: Co-culture microglia downregulate pathogen-response pathways, upregulate homeostatic function pathways, and promote a more anti-inflammatory and pro-remodeling cytokine response than corresponding monocultures, demonstrating that co-cultures are preferable for modeling authentic microglial physiology.
Journal ArticleDOI
Syncytia formation by SARS-CoV-2-infected cells.
Julian Buchrieser,Julian Buchrieser,Jérémy Dufloo,Jérémy Dufloo,Jérémy Dufloo,Mathieu Hubert,Mathieu Hubert,Blandine Monel,Blandine Monel,Delphine Planas,Delphine Planas,Maaran Michael Rajah,Maaran Michael Rajah,Maaran Michael Rajah,Cyril Planchais,Françoise Porrot,Françoise Porrot,Florence Guivel-Benhassine,Florence Guivel-Benhassine,Sylvie van der Werf,Sylvie van der Werf,Nicoletta Casartelli,Nicoletta Casartelli,Hugo Mouquet,Timothée Bruel,Timothée Bruel,Olivier Schwartz,Olivier Schwartz +27 more
TL;DR: The results show that SARS‐CoV‐2 pathological effects are modulated by cellular proteins that either inhibit or facilitate syncytia formation.
Journal ArticleDOI
A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations.
Ludivine Grzelak,Ludivine Grzelak,Sarah Temmam,Cyril Planchais,Caroline Demeret,Laura Tondeur,Christèle Huon,Florence Guivel-Benhassine,Isabelle Staropoli,Maxime Chazal,Jérémy Dufloo,Jérémy Dufloo,Delphine Planas,Julian Buchrieser,Maaran Michael Rajah,Maaran Michael Rajah,Rémy Robinot,Françoise Porrot,Mélanie Albert,Mélanie Albert,Kuang-Yu Chen,Bernadette Crescenzo-Chaigne,Flora Donati,Flora Donati,François Anna,Philippe Souque,Marion Gransagne,Jacques Bellalou,Mireille Nowakowski,Marija Backovic,Lila Bouadma,Lila Bouadma,Lucie Le Fevre,Quentin Le Hingrat,Quentin Le Hingrat,Diane Descamps,Diane Descamps,Annabelle Pourbaix,Cédric Laouénan,Cédric Laouénan,Jade Ghosn,Jade Ghosn,Yazdan Yazdanpanah,Yazdan Yazdanpanah,Camille Besombes,Nathalie Jolly,Sandrine Pellerin-Fernandes,Olivia Chény,Marie Noelle Ungeheuer,Guillaume Mellon,Pascal Morel,Simon Rolland,Félix A. Rey,Sylvie Behillil,Sylvie Behillil,Vincent Enouf,Vincent Enouf,Audrey Lemaitre,Marie Aude Créach,Stéphane Petres,Nicolas Escriou,Pierre Charneau,Arnaud Fontanet,Arnaud Fontanet,Bruno Hoen,Timothée Bruel,Marc Eloit,Hugo Mouquet,Olivier Schwartz,Sylvie van der Werf,Sylvie van der Werf +70 more
TL;DR: Four serological assays measuring anti–SARS-CoV-2 antibodies and their neutralizing activity in samples from individuals with severe and mild COVID-19 are compared and enabled a broad evaluation of SARS- CoV- 2 seroprevalence and antibody profiling in different subpopulations within one region.
Posted ContentDOI
Syncytia formation by SARS-CoV-2 infected cells
Julian Buchrieser,Julian Buchrieser,Jérémy Dufloo,Jérémy Dufloo,Mathieu Hubert,Mathieu Hubert,Blandine Monel,Blandine Monel,Delphine Planas,Delphine Planas,Maaran Michael Rajah,Maaran Michael Rajah,Cyril Planchais,Françoise Porrot,Françoise Porrot,Florence Guivel-Benhassine,Florence Guivel-Benhassine,Sylvie van der Werf,Sylvie van der Werf,Nicoletta Casartelli,Nicoletta Casartelli,Hugo Mouquet,Timothée Bruel,Timothée Bruel,Olivier Schwartz,Olivier Schwartz +25 more
TL;DR: It is shown that SARS-CoV-2 infected cells express the viral Spike protein at their surface and fuse with ACE2-positive neighbouring cells, which facilitates syncytia formation and thwarts the antiviral effect of IFITMs.