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Jade Ghosn

Researcher at University of Paris

Publications -  42
Citations -  3428

Jade Ghosn is an academic researcher from University of Paris. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 11, co-authored 42 publications receiving 1513 citations. Previous affiliations of Jade Ghosn include Pasteur Institute & Claude Bernard University Lyon 1.

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Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

Paul Bastard, +140 more
- 23 Oct 2020 - 
TL;DR: A means by which individuals at highest risk of life-threatening COVID-19 can be identified is identified, and the hypothesis that neutralizing auto-Abs against type I IFNs may underlie critical CO VID-19 is tested.
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Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2 and variants of concern: A narrative review.

TL;DR: In this article, the authors provide an up-to-date comparative analysis of the characteristics, adverse events, efficacy, effectiveness and impact of the variants of concern for nineteen COVID-19 vaccines.
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Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial

Pierre-Louis Tharaux, +600 more
TL;DR: Anakinra did not improve outcomes in patients with mild-to-moderate COVID-19 pneumonia, and further studies are needed to assess the efficacy of anakinra in other selected groups of patients with more severe CO VID-19.
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A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations.

TL;DR: Four serological assays measuring anti–SARS-CoV-2 antibodies and their neutralizing activity in samples from individuals with severe and mild COVID-19 are compared and enabled a broad evaluation of SARS- CoV- 2 seroprevalence and antibody profiling in different subpopulations within one region.
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Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity.

TL;DR: In this paper, the authors studied the immune cell landscape, with emphasis on Mucosal-associated invariant T (MAIT) cells, in cohorts totaling 208 patients with various stages of disease and found that altered MAIT cell functions due to IFN-α-IL-18 imbalance contribute to disease severity, and their therapeutic manipulation may prevent deleterious inflammation in COVID-19 aggravation.