J
Julian Strange
Researcher at University Hospitals Bristol NHS Foundation Trust
Publications - 86
Citations - 2935
Julian Strange is an academic researcher from University Hospitals Bristol NHS Foundation Trust. The author has contributed to research in topics: Percutaneous coronary intervention & Coronary artery disease. The author has an hindex of 21, co-authored 77 publications receiving 2302 citations. Previous affiliations of Julian Strange include National Institute for Health Research & Imperial College London.
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Journal ArticleDOI
Sildenafil versus Endothelin Receptor Antagonist for Pulmonary Hypertension (SERAPH) Study
Martin R. Wilkins,Gideon A. Paul,Julian Strange,Nina Tunariu,Wendy Gin-Sing,Winston Banya,Mark Westwood,Alexander Stefanidis,Leong L. Ng,Dudley J. Pennell,Raad H. Mohiaddin,Petros Nihoyannopoulos,J. Simon R. Gibbs +12 more
TL;DR: Sildenafil added to conventional treatment reduces RV mass and improves cardiac function and exercise capacity in patients with PAH, WHO functional class III.
Journal ArticleDOI
Antiproliferative Effects of Phosphodiesterase Type 5 Inhibition in Human Pulmonary Artery Cells
John Wharton,Julian Strange,Gigi M. O. Møller,Ellena J. Growcott,Xiaohui Ren,Angela P. Franklyn,Stephen C. Phillips,Martin R. Wilkins +7 more
TL;DR: Phosphodiesterase Type 5 is the main factor regulating cyclic guanosine monophosphate hydrolysis and downstream signaling in human PASMCs and the antiproliferative effects of this signaling pathway may be significant in the chronic treatment of pulmonary hypertension with PDE5 inhibitors such as sildenafil.
Journal ArticleDOI
Phosphodiesterase Type 5 as a Target for the Treatment of Hypoxia-Induced Pulmonary Hypertension
TL;DR: PDE5 inhibition attenuates the rise in PAP and vascular remodeling when given before chronic exposure to Hypoxia and when administered as a treatment during ongoing hypoxia-induced pulmonary hypertension.
Journal ArticleDOI
Guiding Principles for Chronic Total Occlusion Percutaneous Coronary Intervention: A Global Expert Consensus Document
Emmanouil S. Brilakis,Kambis Mashayekhi,Etsuo Tsuchikane,Nidal Abi Rafeh,Khaldoon Alaswad,Mario Araya,Alexandre Avran,Lorenzo Azzalini,Avtandil M. Babunashvili,Baktash Bayani,Ravinay Bhindi,Nicolas Boudou,Marouane Boukhris,Nenad Božinović,Leszek Bryniarski,Alexander Bufe,Christopher E. Buller,M. Nicholas Burke,Heinz Joachim Büttner,Pedro Cardoso,Mauro Carlino,Evald Høj Christiansen,Antonio Colombo,Kevin Croce,Félix Damas de los Santos,Tony De Martini,Joseph Dens,Carlo Di Mario,Kefei Dou,Mohaned Egred,Ahmed ElGuindy,Javier Escaned,Sergey Furkalo,Andrea Gagnor,Alfredo R. Galassi,Roberto Garbo,Junbo Ge,Pravin K. Goel,Omer Goktekin,Luca Grancini,J. Aaron Grantham,Colm G. Hanratty,Stefan Harb,Scott A. Harding,José P.S. Henriques,Jonathan Hill,Farouc A. Jaffer,Yangsoo Jang,Risto Jussila,Artis Kalnins,Arun Kalyanasundaram,David E. Kandzari,Hsien Li Kao,Dimitri Karmpaliotis,Hussien Heshmat Kassem,Paul Knaapen,Ran Kornowski,Oleg Krestyaninov,A. V.Ganesh Kumar,Peep Laanmets,Pablo Lamelas,Seung-Whan Lee,Thierry Lefèvre,Yue Li,Soo Teik Lim,Sidney Lo,William Lombardi,Margaret McEntegart,Muhammad Munawar,José A. Navarro Lecaro,Hung M. Ngo,William J. Nicholson,Göran K. Olivecrona,Lucio Padilla,Marin Postu,Alexandre Schaan de Quadros,Franklin Hanna Quesada,Vithala Surya Prakasa Rao,Nicolaus Reifart,Meruzhan Saghatelyan,Ricardo Santiago,George Sianos,Elliot J. Smith,James C. Spratt,Gregg W. Stone,Julian Strange,Khalid Tammam,Imre Ungi,Minh Vo,Vu Hoang Vu,Simon J Walsh,Gerald S. Werner,Jason R Wollmuth,Eugene B. Wu,R. Michael Wyman,Bo Xu,Masahisa Yamane,Luiz F. Ybarra,Robert W. Yeh,Qi Zhang,Stéphane Rinfret +100 more
TL;DR: In this paper, the authors identified seven common principles that are widely accepted as best practices for chronic total occlusion percutaneous coronary intervention (PCI) in CTO-PCI.
Journal ArticleDOI
The Hybrid Algorithm for Treating Chronic Total Occlusions in Europe The RECHARGE Registry
Joren Maeremans,Simon J Walsh,Paul Knaapen,James C. Spratt,Alexandre Avran,Colm G. Hanratty,Benjamin Faurie,Pierfrancesco Agostoni,Erwan Bressollette,Peter Kayaert,Alan Bagnall,Mohaned Egred,Dave Smith,Alexander Chase,Margaret McEntegart,William Smith,Alun Harcombe,Paul Kelly,John Irving,Elliot J. Smith,Julian Strange,Joseph Dens +21 more
TL;DR: High procedure and patient success rates, combined with a low event rate and improved procedural characteristics, support further use of the hybrid algorithm for a broad community of appropriately trained CTO operators.