Julius Cranshaw

TL;DR: Quality of life was good and similar in patients with cardiac arrest receiving targeted temperature management at 33°C or 36°C and cognitive function was similar in both intervention groups, but many patients and observers reported impairment not detected previously by standard outcome scales.

TL;DR: The TTM trial will investigate potential benefit and harm of 2 target temperature strategies, both avoiding hyperthermia in a large proportion of the out-of-hospital cardiac arrest population.

TL;DR: Delayed prognostication was relevant for a minority of patients and related to subsequent decisions on level-of-care with effects on ICU length- of-stay, survival time and outcome.

TL;DR: In this article , two acute respiratory distress syndrome (ARDS) subphenotypes (hyperinflammatory and hypoinflammatory) with distinct clinical and biological features and differential treatment responses have been identified using latent class analysis (LCA) in seven individual cohorts.

TL;DR: Higher blood glucose levels at admission and during the first 36 hours, and higher glycemic variability, were associated with poor neurologic outcome and death.