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Amita Aggarwal
Researcher at Stanford University
Publications - 5
Citations - 8314
Amita Aggarwal is an academic researcher from Stanford University. The author has contributed to research in topics: Genome & Human genome. The author has an hindex of 5, co-authored 5 publications receiving 7677 citations.
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Journal ArticleDOI
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Roger E. McLendon,Allan H. Friedman,Darrell D. Bigner,Erwin G. Van Meir,Daniel J. Brat,Gena M. Mastrogianakis,Jeffrey J. Olson,Tom Mikkelsen,Norman L. Lehman,Kenneth Aldape,W. K. Alfred Yung,Oliver Bogler,John N. Weinstein,Scott R. VandenBerg,Mitchel S. Berger,Michael D. Prados,Donna M. Muzny,Margaret Morgan,Steve Scherer,Aniko Sabo,Lynn Nazareth,Lora Lewis,Otis Hall,Yiming Zhu,Yanru Ren,Omar Alvi,Jiqiang Yao,Alicia Hawes,Shalini N. Jhangiani,Gerald R. Fowler,Anthony San Lucas,Christie Kovar,Andrew Cree,Huyen Dinh,Jireh Santibanez,Vandita Joshi,Manuel L. Gonzalez-Garay,Christopher A. Miller,Aleksandar Milosavljevic,Lawrence A. Donehower,David A. Wheeler,Richard A. Gibbs,Kristian Cibulskis,Carrie Sougnez,Timothy Fennell,Scott Mahan,Jane Wilkinson,Liuda Ziaugra,Robert C. Onofrio,Toby Bloom,Rob Nicol,Kristin G. Ardlie,Jennifer Baldwin,Stacey Gabriel,Eric S. Lander,Eric S. Lander,Li Ding,Robert S. Fulton,Michael D. McLellan,John W. Wallis,David E. Larson,Xiaoqi Shi,Rachel Abbott,Lucinda Fulton,Ken Chen,Daniel C. Koboldt,Michael C. Wendl,Rick Meyer,Yuzhu Tang,Ling Lin,John R. Osborne,Brian H. Dunford-Shore,Tracie L. Miner,Kim D. Delehaunty,Chris Markovic,Gary W. Swift,William Courtney,Craig Pohl,Scott Abbott,Amy Hawkins,Shin Leong,Carrie A. Haipek,Heather Schmidt,Maddy Wiechert,Tammi L. Vickery,Sacha Scott,David J. Dooling,Asif T. Chinwalla,George M. Weinstock,Elaine R. Mardis,Richard K. Wilson,Gad Getz,Wendy Winckler,Roel G.W. Verhaak,Michael S. Lawrence,Michael J. T. O’Kelly,James A. Robinson,Gabriele Alexe,Rameen Beroukhim,Scott L. Carter,Derek Y. Chiang,Josh Gould,Supriya Gupta,Josh Korn,Craig H. Mermel,Jill P. Mesirov,Stefano Monti,Huy V. Nguyen,Melissa Parkin,Michael R. Reich,Nicolas Stransky,Barbara A. Weir,Levi A. Garraway,Todd R. Golub,Matthew Meyerson,Lynda Chin,Alexei Protopopov,Jianhua Zhang,Ilana Perna,Sandy Aronson,Narayanan Sathiamoorthy,Georgia Ren,Jun Yao,W. Ruprecht Wiedemeyer,Hyun Soo Kim,Won Kong Sek,Yonghong Xiao,Isaac S. Kohane,Jon G. Seidman,Peter J. Park,Raju Kucherlapati,Peter W. Laird,Leslie Cope,James G. Herman,Daniel J. Weisenberger,Fei Pan,David Van Den Berg,Leander Van Neste,Mi Yi Joo,Kornel E. Schuebel,Stephen B. Baylin,Devin Absher,Jun Li,Audrey Southwick,Shannon T. Brady,Amita Aggarwal,Tisha Chung,Gavin Sherlock,James D. Brooks,Richard M. Myers,Paul T. Spellman,Elizabeth Purdom,Lakshmi Jakkula,Anna Lapuk,Henry Marr,Shannon Dorton,Gi Choi Yoon,Ju Han,Amrita Ray,Victoria Wang,Steffen Durinck,Mark D. Robinson,Nicholas J. Wang,Karen Vranizan,Vivian Peng,Eric Van Name,Gerald V. Fontenay,John Ngai,John G. Conboy,Bahram Parvin,Heidi S. Feiler,Terence P. Speed,Terence P. Speed,Joe W. Gray,Cameron Brennan,Nicholas D. Socci,Adam B. Olshen,Barry S. Taylor,Barry S. Taylor,Alex E. Lash,Nikolaus Schultz,Boris Reva,Yevgeniy Antipin,Alexey Stukalov,Benjamin Gross,Ethan Cerami,Qing Wang Wei,Li-Xuan Qin,Venkatraman E. Seshan,Liliana Villafania,Magali Cavatore,Laetitia Borsu,Agnes Viale,William L. Gerald,Chris Sander,Marc Ladanyi,Charles M. Perou,D. Neil Hayes,Michael D. Topal,Katherine A. Hoadley,Yuan Qi,Sai Balu,Yan Shi,Junyuan Wu,Robert Penny,Michael L. Bittner,Troy Shelton,Elizabeth Lenkiewicz,Scott Morris,Debbie Beasley,Sheri Sanders,Ari B. Kahn,Robert Sfeir,Jessica Chen,David Nassau,Larry Feng,Erin Hickey,Anna D. Barker,Daniela S. Gerhard,Joseph G. Vockley,Carolyn C. Compton,Jim Vaught,Peter Fielding,Martin L. Ferguson,Carl F. Schaefer,Jinghui Zhang,Subhashree Madhavan,Kenneth H. Buetow,Francis S. Collins,Peter J. Good,Mark S. Guyer,Brad Ozenberger,Jane Peterson,Elizabeth J. Thomson +233 more
TL;DR: The interim integrative analysis of DNA copy number, gene expression and DNA methylation aberrations in 206 glioblastomas reveals a link between MGMT promoter methylation and a hypermutator phenotype consequent to mismatch repair deficiency in treated gliobeasts, demonstrating that it can rapidly expand knowledge of the molecular basis of cancer.
Journal ArticleDOI
A gene map of the human genome
Gregory D. Schuler,Mark S. Boguski,Elizabeth A. Stewart,Lincoln Stein,Gabor Gyapay,Kate Rice,Robert E. White,P. Rodriguez-Tomé,Amita Aggarwal,Eva Bajorek,S. Bentolila,B. B. Birren,Adam Butler,Andrew B. Castle,N. Chiannilkulchai,Angela M. Chu,C M Clee,Sid Cowles,P. J. R. Day,T. Dibling,N. Drouot,Ian Dunham,Simone Duprat,C. East,C A Edwards,Jun Fan,Nicole Y. Fang,Cécile Fizames,Christine Garrett,L. Green,David Hadley,Midori A. Harris,Paul Harrison,Shannon T. Brady,Andrew A. Hicks,E. Holloway,L. Hui,S. Hussain,C. Louis-Dit-Sully,J. Ma,A. MacGilvery,Christopher Mader,A. Maratukulam,Tara C. Matise,K. B. McKusick,Jean Morissette,Andrew J. Mungall,Delphine Muselet,H. C. Nusbaum,David C. Page,Ammon B. Peck,Shanti M. Perkins,Mark Piercy,Fawn Qin,John Quackenbush,S A Ranby,Tim Reif,Steve Rozen,C. Sanders,X. She,James Silva,Donna K. Slonim,Carol Soderlund,W.-L. Sun,P. Tabar,T. Thangarajah,Nathalie Vega-Czarny,Douglas Vollrath,S. Voyticky,T. E. Wilmer,Xiao-Yu Wu,Mark Raymond Adams,Charles Auffray,Nicole A.R. Walter,Rhonda Brandon,Anindya Dehejia,Peter N. Goodfellow,R. Houlgatte,James R. Hudson,Susan E. Ide,K. R. Iorio,Wha‐Young Lee,N. Seki,Takahiro Nagase,K. Ishikawa,N. Nomura,Cheryl Phillips,Mihael H. Polymeropoulos,Mina Sandusky,Karin Schmitt,Richard Berry,K. Swanson,R. Torres,J. C. Venter,James M. Sikela,Jacques S. Beckmann,Jean Weissenbach,Richard M. Myers,David R. Cox,Michael R. James,David Bentley,Panos Deloukas,Eric S. Lander,Thomas J. Hudson,Thomas J. Hudson +104 more
TL;DR: The gene map unifies the existing genetic and physical maps with the nucleotide and protein sequence databases in a fashion that should speed the discovery of genes underlying inherited human disease.
Journal ArticleDOI
An STS-Based Radiation Hybrid Map of the Human Genome
Elizabeth A. Stewart,Kathleen B. McKusick,Amita Aggarwal,Ewa Bajorek,Shannon T. Brady,Angela Chu,Nicole Y. Fang,David Hadley,Mark Harris,Sami Hussain,Sami Hussain,Richard S. Lee,Annu Maratukulam,Kyle O'Connor,Kyle O'Connor,Shanti M. Perkins,Mark Piercy,Fawn Qin,Tim Reif,Carla Sanders,Xiaohong She,Wei Lin Sun,Poroshat Tabar,Susan Voyticky,Sid Cowles,Sid Cowles,Jian Bing Fan,Jian Bing Fan,Christopher Mader,John Quackenbush,Richard M. Myers,David R. Cox +31 more
TL;DR: This STS-based radiation hybrid map of the human genome brings us one step closer to the goal of a physical map containing 30,000 unique ordered landmarks with an average marker spacing of 100 kb.
Journal ArticleDOI
A high-resolution radiation hybrid map of the human genome draft sequence
Michael Olivier,Amita Aggarwal,Jennifer Allen,Annalisa A. Almendras,Eva Bajorek,Ellen M. Beasley,Shannon D. Brady,Jannette M. Bushard,Valerie I. Bustos,Angela Chu,Tisha R. Chung,Anniek de Witte,Mirian Denys,Rakly Dominguez,Nicole Y. Fang,Brian D. Foster,Robert W. Freudenberg,David Hadley,Libby R. Hamilton,Tonya J. Jeffrey,Libusha Kelly,Laura C. Lazzeroni,Michelle R. Levy,Saskia C. Lewis,Xia Liu,Frederick Lopez,Brent Louie,Joseph P. Marquis,Robert A. Martinez,Margaret K. Matsuura,Nedda S. Misherghi,Jolanna A. Norton,Adam B. Olshen,Shanti M. Perkins,Amy J. Perou,Christopher Piercy,Mark Piercy,Fawn Qin,Tim Reif,Kelly Sheppard,Vida Shokoohi,Geoff A. Smick,Wei-Lin Sun,Elizabeth A. Stewart,J. Fernando,Tejeda,Nguyet M. Tran,Tonatiuh Trejo,Nu T. Vo,Simon C. M. Yan,Deborah L. Zierten,Shaying Zhao,Ravi Sachidanandam,Barbara J. Trask,Richard M. Myers,David R. Cox +55 more
TL;DR: A physical map of the human genome is constructed by using a panel of 90 whole-genome radiation hybrids (the TNG panel) in conjunction with 40,322 sequence-tagged sites (STSs) derived from random genomic sequences as well as expressed sequences.
Journal ArticleDOI
Complex high-resolution linkage disequilibrium and haplotype patterns of single-nucleotide polymorphisms in 2.5 Mb of sequence on human chromosome 21.
Michael Olivier,Michael Olivier,Valerie I. Bustos,Michelle R. Levy,Geoff A. Smick,I. Moreno,Jannette M. Bushard,Annalisa A. Almendras,Kelly Sheppard,Deborah L. Zierten,Amita Aggarwal,Chris Carlson,Chris Carlson,Brian D. Foster,Nu Vo,Libusha Kelly,Xia Liu,David R. Cox +17 more
TL;DR: The results indicate that LD and haplotype patterns need to be investigated with closely spaced SNPs throughout the human genome, independent of the location of coding sequences, to reliably identify regions with significant LD useful for disease association studies.