scispace - formally typeset
J

Jun He

Researcher at Tianjin University of Traditional Chinese Medicine

Publications -  99
Citations -  2805

Jun He is an academic researcher from Tianjin University of Traditional Chinese Medicine. The author has contributed to research in topics: High-performance liquid chromatography & Cancer. The author has an hindex of 24, co-authored 96 publications receiving 2090 citations. Previous affiliations of Jun He include Thomas Jefferson University & Nanjing Medical University.

Papers
More filters
Journal ArticleDOI

A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1

Qing Xu, +15 more
- 01 Feb 2013 - 
TL;DR: It is demonstrated that IGF-IR and IRS1, often overexpressed in BC, are two novel targets of miR-148a/152, and that restoration of microRNAs expression may provide a strategy for therapeutic application to treat BC patients.
Journal ArticleDOI

MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers.

Xu Qian, +15 more
- 08 Apr 2013 - 
TL;DR: Levels in human blood and tumor tissues are associated with CRC cancer occurrence, metastasis and drug resistance, and miR-143 levels may be used as a new diagnostic marker and therapeutic target for CRC in the future.
Journal ArticleDOI

Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy

Jun He, +6 more
- 04 Feb 2015 - 
TL;DR: MIR152 is reported as a new autophagy-regulating miRNA that plays a role in cisplatin-resistance and it is found that EGR1 (early growth response 1) regulated the MIR152 gene at the transcriptional level.
Journal ArticleDOI

Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells

Wan Li, +8 more
- 19 May 2016 - 
TL;DR: Analysis of lncRNA expression in human NSCLC samples by using microarray data from Gene Expression Omnibus indicates that AGAP2-AS1 may act as an oncogene by repressing tumor-suppressor LATS2 and KLF2 transcription.
Journal ArticleDOI

Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR‐199a/125b and DNA methylation

Jun He, +13 more
- 01 Dec 2012 - 
TL;DR: It is shown that reactive oxygen species (ROS) induce both ERBB2 and ERBB3 expression in vitro and in vivo, and that ERBB 2 and ER BB3 expression is regulated by ROS via miR‐199a and miR-125b downregulation and DNA hypermethylation.