K. Farrugia

TL;DR: In this paper , the authors evaluated the ability of several B.1.529 isolates to cause infection and disease in immunocompetent and human ACE2 (hACE2)-expressing mice and hamsters.

TL;DR: This assay demonstrated variant-specific signatures of nucleotide/amino acid polymorphisms and underscored its utility for the detection of contemporary and emerging SARS-CoV-2 variants of concern and highlighted distinct target patterns that could be utilized to identify variants not yet defined on the panel.

TL;DR: These findings exemplify the power of highly multiplexed diagnostic panels to accurately call variants and the potential for target result signatures to elucidate new ones.

TL;DR: In this article , the authors describe sequential persistent SARS-CoV-2 infections in three individuals that led to the emergence, forward transmission, and continued evolution of a new Omicron sublineage, BA.1.23, over an eight-month period.

TL;DR: In this paper , the authors conducted a genomic analysis of 23 infected patients from New York City during the early outbreak of MPV and compared the genomic sequences of clinical isolates versus culture-passaged samples from a subset of samples.