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Samantha Loeber
Researcher at University of Wisconsin-Madison
Publications - 16
Citations - 1502
Samantha Loeber is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 4 publications receiving 453 citations.
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Journal ArticleDOI
Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development.
Masaki Imai,Kiyoko Iwatsuki-Horimoto,Masato Hatta,Samantha Loeber,Peter Halfmann,Noriko Nakajima,Tokiko Watanabe,Michiko Ujie,Kenta Takahashi,Mutsumi Ito,Shinya Yamada,Shufang Fan,Shiho Chiba,Makoto Kuroda,Lizheng Guan,Kosuke Takada,Tammy Armbrust,Aaron Balogh,Yuri Furusawa,Moe Okuda,Hiroshi Ueki,Atsuhiro Yasuhara,Yuko Sakai-Tagawa,Tiago J. S. Lopes,Tiago J. S. Lopes,Maki Kiso,Seiya Yamayoshi,Noriko Kinoshita,Norio Ohmagari,Shin-ichiro Hattori,Makoto Takeda,Hiroaki Mitsuya,Florian Krammer,Tadaki Suzuki,Yoshihiro Kawaoka,Yoshihiro Kawaoka +35 more
TL;DR: It is found that SARS-CoV-2 isolates replicate efficiently in the lungs of Syrian hamsters and cause severe pathological lesions in the lung of these animals similar to commonly reported imaging features of COVID-19 patients with pneumonia.
Journal ArticleDOI
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters
Peter Halfmann,Shun Iida,Kiyoko Iwatsuki-Horimoto,Tadashi Maemura,Maki Kiso,Suzanne M. Scheaffer,Tamarand L. Darling,Astha Joshi,Samantha Loeber,Gagandeep Singh,Stephanie L. Foster,Baoling Ying,James Brett Case,Zhenlu Chong,Bradley M. Whitener,Juan I. Moliva,Katharine Floyd,Michiko Ujie,Noriko Nakajima,Mutsumi Ito,R. Wright,Ryuta Uraki,Prajakta Warang,Matthew Gagne,Rongxiu Li,Yuko Sakai-Tagawa,Yanan Liu,Deanna Larson,Jorge E. Osorio,Juan P. Hernández-Ortiz,Amy R. Henry,Karl A Ciuoderis,Kelsey Florek,Mit Patel,Abby E. Odle,Lok-Yin Roy Wong,Allen C. Bateman,Zhongde Wang,Venkata Viswanadh Edara,John Franks,Trushar Jeevan,Thomas P. Fabrizio,Jennifer DeBeauchamp,Lisa Kercher,Patrick Seiler,Ana S. Gonzalez-Reiche,Emilia Mia Sordillo,Lauren A. Chang,Harm van Bakel,Viviana Simon,Bremy Alburquerque,Hala Alshammary,Angela Amoako,Shiraz Aslam,Radhika N. Banu,Cecilia Cognigni,Marlene Espinoza-Moraga,K. Farrugia,Adriana van de Guchte,Z. Khalil,Manon Laporte,Ignacio Mena,Alberto Paniz-Mondolfi,Jose Polanco,A.A. “Sonny” Rooker,L. Sominsky,Daniel C. Douek,Nancy J. Sullivan,Larissa B. Thackray,Hiroshi Ueki,Seiya Yamayoshi,Masaki Imai,Stanley Perlman,Richard J. Webby,Robert A. Seder,Mehul S. Suthar,Adolfo García-Sastre,Michael Schotsaert,Tadaki Suzuki,Adrianus C. M. Boon,Michael S. Diamond,Yoshihiro Kawaoka +81 more
TL;DR: In this paper , the authors evaluated the ability of several B.1.529 isolates to cause infection and disease in immunocompetent and human ACE2 (hACE2)-expressing mice and hamsters.
Journal ArticleDOI
Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA.2
Ryuta Uraki,Maki Kiso,Shun Iida,Masaki Imai,Emi Takashita,Makoto Kuroda,Peter Halfmann,Samantha Loeber,Tadashi Maemura,Seiya Yamayoshi,Seiichiro Fujisaki,Zhongde Wang,Mutsumi Ito,Michiko Ujie,Kiyoko Iwatsuki-Horimoto,Yuri Furusawa,R. Wright,Zhenlu Chong,Seiya Ozono,Atsuhiro Yasuhara,Hiroshi Ueki,Yuko Sakai-Tagawa,Rongxiu Li,Yanan Liu,Deanna Larson,Michiko Koga,Takeya Tsutsumi,Eisuke Adachi,Makoto Saito,Shinya Yamamoto,Masao Hagihara,Keiko Mitamura,Tetsuro Sato,Masayuki Hojo,Shin-ichiro Hattori,Kenji Maeda,Riccardo Valdez,Pamela E. Bennett-Baker,Zijin Chu,Dawson Davis,Theresa Kowalski-Dobson,Ashley Eckard,Carmen Gherasim,Wolf Gremel,Kathy Lindsey,David M Manthei,A. Meyers,Julio Zuniga Moya,Aaron Rico,Emily Stoneman,Victoria Le Blanc,Savanna Sneeringer,Lauren Warsinske,Moe Okuda,Jurika Murakami,C. Duong,Sucheta Godbole,Daniel C. Douek,Ken Maeda,Shinji Watanabe,Aubree Gordon,Norio Ohmagari,Hiroshi Yotsuyanagi,Michael S. Diamond,Hideki Hasegawa,Hiroaki Mitsuya,Tadaki Suzuki,Yoshihiro Kawaoka +67 more
TL;DR: In this article , the authors evaluated the replicative ability and pathogenicity of authentic infectious BA.2 isolates in immunocompetent and human ACE2-expressing mice and hamsters.
Posted ContentDOI
Characterization and antiviral susceptibility of SARS-CoV-2 Omicron/BA.2
Yoshihiro Kawaoka,Ryuta Uraki,Maki Kiso,Shun Iida,Masaki Imai,Emi Takashita,Makoto Kuroda,Peter Halfmann,Samantha Loeber,Tadashi Maemura,Seiya Yamayoshi,Seiichiro Fujisaki,Zhongde Wang,Mutsumi Ito,Michiko Ujie,Kiyoko Iwatsuki-Horimoto,Yuri Furusawa,R. Wright,Zhenlu Chong,Seiya Ozono,Atsuhiro Yasuhara,Hiroshi Ueki,Yuko Sakai,Rongxiu Li,Yanan Liu,Deanna Larson,Michiko Koga,Takeya Tsutsumi,Eisuke Adachi,Makoto Saito,Shinya Yamamoto,Shohei Matsubara,Masao Hagihara,Keiko Mitamura,Tetsuro Sato,Masayuki Hojo,Shin-ichiro Hattori,Kenji Maeda,Moe Okuda,Jurika Murakami,C. Duong,Sucheta Godbole,Daniel C. Douek,Shinji Watanabe,Norio Ohmagari,Hiroshi Yotsuyanagi,Michael S. Diamond,Hideki Hasegawa,Hiroaki Mitsuya,Tadaki Suzuki +49 more
TL;DR: Findings suggest that the replication and pathogenicity of BA.2 is comparable to that ofBA.1 in rodents and that several therapeutic monoclonal antibodies and antiviral compounds are effective against Omicron/BA.2 variants.
Journal ArticleDOI
Characterization of a new SARS-CoV-2 variant that emerged in Brazil.
Masaki Imai,Peter Halfmann,Seiya Yamayoshi,Kiyoko Iwatsuki-Horimoto,Shiho Chiba,Tokiko Watanabe,Noriko Nakajima,Mutsumi Ito,Makoto Kuroda,Maki Kiso,Tadashi Maemura,Kenta Takahashi,Samantha Loeber,Masato Hatta,Michiko Koga,Hiroyuki Nagai,Shinya Yamamoto,Makoto Saito,Eisuke Adachi,Osamu Akasaka,Morio Nakamura,Ichiro Nakachi,Takayuki Ogura,Rie Baba,Kensuke Fujita,Junichi Ochi,Keiko Mitamura,Hideaki Kato,Hideaki Nakajima,Kazuma Yagi,Shin ichiro Hattori,Kenji Maeda,Tetsuya Suzuki,Yusuke Miyazato,Riccardo Valdez,Carmen Gherasim,Yuri Furusawa,Moe Okuda,Michiko Ujie,Tiago J. S. Lopes,Atsuhiro Yasuhara,Hiroshi Ueki,Yuko Sakai-Tagawa,Amie J. Eisfeld,John J. Baczenas,David A. Baker,Shelby L. O’Connor,David H. O’Connor,Shuetsu Fukushi,Tsuguto Fujimoto,Yudai Kuroda,Aubree Gordon,Ken Maeda,Norio Ohmagari,Norio Sugaya,Hiroshi Yotsuyanagi,Hiroaki Mitsuya,Tadaki Suzuki,Yoshihiro Kawaoka,Yoshihiro Kawaoka +59 more
TL;DR: In this paper, the authors characterized a P.1 variant isolated in Japan by using Syrian hamsters, a well-established small animal model for the study of SARS-CoV-2 disease (COVID-19).