K
Kai Huang
Researcher at University of Texas Medical Branch
Publications - 47
Citations - 2688
Kai Huang is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Ebolavirus & Epitope. The author has an hindex of 20, co-authored 44 publications receiving 2329 citations. Previous affiliations of Kai Huang include International Institute of Minnesota & Li Ka Shing Faculty of Medicine, University of Hong Kong.
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Journal ArticleDOI
Establishment of multiple sublineages of H5N1 influenza virus in Asia: Implications for pandemic control
Honglin Chen,Gavin J. D. Smith,Gavin J. D. Smith,K. S. Li,Jia Wang,Xiaohui Fan,J. M. Rayner,J. M. Rayner,Dhanasekaran Vijaykrishna,Dhanasekaran Vijaykrishna,Jinxia Zhang,Jinxia Zhang,L. J. Zhang,L. J. Zhang,C. T. Guo,C. L. Cheung,C. L. Cheung,K. M. Xu,K. M. Xu,Lian Duan,Lian Duan,Kai Huang,K. Qin,K. Qin,Y. H. C. Leung,Wai Lan Wu,Wai Lan Wu,Hongjing Lu,Yongxiong Chen,Ningshao Xia,T. S. P. Naipospos,Kwok-Yung Yuen,Sharifah Syed Hassan,S. Bahri,Toan D. Nguyen,Robert G. Webster,Joseph S. M. Peiris,Joseph S. M. Peiris,Yi Guan,Yi Guan +39 more
TL;DR: It is reported that genetically and antigenically distinct sublineages of H5N1 virus have become established in poultry in different geographical regions of Southeast Asia, indicating the long-term endemicity of the virus, and the isolation of H3N2 virus from apparently healthy migratory birds in southern China.
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Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance
Yunwen Hu,Shuihua Lu,Zhigang Song,Wei Wang,Pei Hao,Pei Hao,Jianhua Li,Xiaonan Zhang,Hui-Ling Yen,Bisheng Shi,Tao Li,Wencai Guan,Lei Xu,Yi Liu,Sen Wang,Xiaoling Zhang,Di Tian,Zhaoqin Zhu,Jing He,Kai Huang,Huijie Chen,Lulu Zheng,Xuan Li,Jie Ping,Jie Ping,Bin Kang,Xiuhong Xi,Li-jun Zha,Yixue Li,Zhiyong Zhang,Malik Peiris,Zhenghong Yuan +31 more
TL;DR: The emergence of antiviral resistance in A/H7N9 viruses, especially in patients receiving corticosteroid therapy, is concerning, needs to be closely monitored, and considered in pandemic preparedness planning.
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Emergence and predominance of an H5N1 influenza variant in China
Gavin J. D. Smith,Xiaohui Fan,Jin Wang,Kenneth S. M. Li,K. Qin,Jinxia Zhang,Dhanasekaran Vijaykrishna,CL Cheung,Kai Huang,J. M. Rayner,Joseph S. M. Peiris,Honglin Chen,Robert G. Webster,Yi Guan +13 more
TL;DR: Genetic and antigenic analyses revealed the emergence and predominance of a previously uncharacterized H5N1 virus sublineage (Fujian-like) in poultry since late 2005, resulting in a new transmission and outbreak wave in Southeast Asia.
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The genome of Mesobuthus martensii reveals a unique adaptation model of arthropods
Zhijian Cao,Yao Yu,Yingliang Wu,Pei-Pei Hao,Zhiyong Di,Yawen He,Zongyun Chen,Weishan Yang,Zhiyong Shen,Xiaohua He,Jia Sheng,Xiaobo Xu,Bohu Pan,Jing Feng,Xiaojuan Yang,Wei Hong,Wenjuan Zhao,Zhongjie Li,Kai Huang,Tian-tian Li,Yimeng Kong,Hui Liu,Dahe Jiang,Binyan Zhang,Jun Hu,Youtian Hu,Bin-Bin Wang,Jianliang Dai,Bi-Feng Yuan,Yu-Qi Feng,Wei Huang,Xiaojing Xing,Guoping Zhao,Xuan Li,Yixue Li,Wenxin Li +35 more
TL;DR: The genome sequence of Mesobuthus martensii is reported, containing 32,016 protein-coding genes, the most among sequenced arthropods, and reveals a unique adaptation model of arthropod, offering new insights into the genetic bases of the living fossils.
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The development and genetic diversity of H5N1 influenza virus in China, 1996-2006.
Lian Duan,Justin Bahl,Justin Bahl,Gavin J. D. Smith,Gavin J. D. Smith,Junwen Wang,Junwen Wang,Dhanasekaran Vijaykrishna,Dhanasekaran Vijaykrishna,L. J. Zhang,L. J. Zhang,Jinxia Zhang,Jinxia Zhang,K. S. Li,Xiaohui Fan,CL Cheung,Kai Huang,Leo L.M. Poon,Kennedy F. Shortridge,Kennedy F. Shortridge,Robert G. Webster,Joseph S. M. Peiris,Honglin Chen,Honglin Chen,Yi Guan,Yi Guan +25 more
TL;DR: This phylogenetically analyzed H5N1 virus genomes isolated from 1996 to 2006 in this region revealed two major group reassortment events in 2001 and 2002 that were responsible for the generation of the majority of the 44 distinct Gs/GD genotypes identified.