K
Kai P. Yuet
Researcher at Massachusetts Institute of Technology
Publications - 15
Citations - 1918
Kai P. Yuet is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Proteome & Protein engineering. The author has an hindex of 13, co-authored 15 publications receiving 1768 citations. Previous affiliations of Kai P. Yuet include California Institute of Technology.
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Journal ArticleDOI
PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery.
Juliana M. Chan,Liangfang Zhang,Kai P. Yuet,Grace V. Liao,June-Wha Rhee,Robert Langer,Omid C. Farokhzad +6 more
TL;DR: The data suggest that the PLGA-lecithin-PEG core-shell NPs may be a useful new controlled release drug delivery system.
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Superparamagnetic Iron Oxide Nanoparticle-Aptamer Bioconjugates for Combined Prostate Cancer Imaging and Therapy
Andrew Z. Wang,Andrew Z. Wang,Vaishali Bagalkot,Christophoros C. Vasilliou,Frank X. Gu,Frank Alexis,Frank Alexis,Liangfang Zhang,Mariam R Shaikh,Kai P. Yuet,Michael J. Cima,Robert Langer,Philip W. Kantoff,Neil H. Bander,Sangyong Jon,Omid C. Farokhzad +15 more
TL;DR: A novel, multifunc-tional, thermally cross-linked SPION (TCL-SPION) that can both detect PCa cells, and deliver targeted chemotherapeuticagents directly to the PCa Cells is reported.
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Multifunctional Superparamagnetic Janus Particles
TL;DR: Although these monodisperse particles find immediate use in tissue engineering, their ability to self-assemble with tunable anisotropic configurations makes them an intriguing material for several exciting areas of research such as photonic crystals, novel microelectronic architecture, and sensing.
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Spatiotemporal controlled delivery of nanoparticles to injured vasculature
Juliana M. Chan,Liangfang Zhang,Rong Tong,Debadyuti Ghosh,Weiwei Gao,Grace V. Liao,Kai P. Yuet,David S. Gray,June-Wha Rhee,Jianjun Cheng,Gershon Golomb,Peter Libby,Robert Langer,Omid C. Farokhzad +13 more
TL;DR: The nanoparticles inhibited human aortic smooth muscle cell proliferation in vitro and showed greater in vivo vascular retention during percutaneous angioplasty over nontargeted controls, which may potentially be used toward the treatment of injured vasculature.
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Synthesis of Nonspherical Superparamagnetic Particles: In Situ Coprecipitation of Magnetic Nanoparticles in Microgels Prepared by Stop-Flow Lithography
TL;DR: Particles with spatially segregated domains of varying magnetic properties (e.g., Janus particles, particles with step changes in magnetite concentration, etc.) can be synthesized readily using this approach.