K
Karl Werdan
Researcher at Martin Luther University of Halle-Wittenberg
Publications - 554
Citations - 20671
Karl Werdan is an academic researcher from Martin Luther University of Halle-Wittenberg. The author has contributed to research in topics: Cardiogenic shock & Myocardial infarction. The author has an hindex of 66, co-authored 539 publications receiving 18780 citations. Previous affiliations of Karl Werdan include Hochschule Hannover & Heidelberg University.
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Journal ArticleDOI
Intraaortic Balloon Support for Myocardial Infarction with Cardiogenic Shock
Holger Thiele,Uwe Zeymer,Franz-Josef Neumann,Miroslaw Ferenc,Hans-Georg Olbrich,Jörg Hausleiter,Gert Richardt,Marcus Hennersdorf,Klaus Empen,Georg Fuernau,Steffen Desch,Ingo Eitel,Rainer Hambrecht,Jörg Fuhrmann,Michael Böhm,Henning Ebelt,Steffen Schneider,Gerhard Schuler,Karl Werdan +18 more
TL;DR: The use of intraaortic balloon counterpulsation did not significantly reduce 30-day mortality in patients with cardiogenic shock complicating acute myocardial infarction for whom an early revascularization strategy was planned.
Journal ArticleDOI
Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial
John R. Teerlink,Gad Cotter,Beth A. Davison,G. Michael Felker,Gerasimos Filippatos,Barry H. Greenberg,Piotr Ponikowski,Elaine Unemori,Adriaan A. Voors,Kirkwood F. Adams,Maria Dorobantu,Liliana Grinfeld,Guillaume Jondeau,Alon Marmor,Josep Masip,Peter S. Pang,Karl Werdan,Sam L. Teichman,Angelo J. Trapani,Christopher Bush,Rajnish Saini,Christoph Schumacher,Thomas Severin,Marco Metra +23 more
TL;DR: Treatment of acute heart failure with serelaxin was associated with dyspnoea relief and improvement in other clinical outcomes, but had no effect on readmission to hospital.
Journal ArticleDOI
Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial
Holger Thiele,Uwe Zeymer,Franz-Josef Neumann,Miroslaw Ferenc,Hans-Georg Olbrich,Jörg Hausleiter,Antoinette de Waha,Gert Richardt,Marcus Hennersdorf,Klaus Empen,Georg Fuernau,Steffen Desch,Ingo Eitel,Rainer Hambrecht,Bernward Lauer,Michael Böhm,Henning Ebelt,Steffen Schneider,Karl Werdan,Gerhard Schuler +19 more
TL;DR: In patients undergoing early revascularisation for myocardial infarction complicated by cardiogenic shock, IABP did not reduce 12 month all-cause mortality.
Journal ArticleDOI
Alkalization of the Chloroplast Stroma Caused by Light-Dependent Proton Flux Into the Thylakoid Space
TL;DR: It is discussed that the light-dependent alkalization in the chloroplast stroma may be involved in the regulation of CO2 fixation at the fructose diphosphatase step.
Journal ArticleDOI
Meta-analysis of genome-wide association studies in >80,000 subjects identifies multiple loci for C-reactive protein levels
Abbas Dehghan,Josée Dupuis,Josée Dupuis,Maja Barbalić,Joshua C. Bis,Gudny Eiriksdottir,Chen Lu,Niina Pellikka,Henri Wallaschofski,Johannes Kettunen,Peter Henneman,Jens Baumert,David P. Strachan,Christian Fuchsberger,Veronique Vitart,James F. Wilson,Guillaume Paré,Silvia Naitza,Megan E. Rudock,Ida Surakka,Eco J. C. de Geus,Behrooz Z. Alizadeh,Jack M. Guralnik,Alan R. Shuldiner,Toshiko Tanaka,Robert Y.L. Zee,Renate B. Schnabel,Vijay Nambi,Maryam Kavousi,Samuli Ripatti,Matthias Nauck,Nicholas L. Smith,Albert V. Smith,Jouko Sundvall,Paul Scheet,Yongmei Liu,Aimo Ruokonen,Lynda M. Rose,Martin G. Larson,Martin G. Larson,Ron C. Hoogeveen,Nelson B. Freimer,Alexander Teumer,Russell P. Tracy,Lenore J. Launer,Julie E. Buring,Jennifer F. Yamamoto,Jennifer F. Yamamoto,Aaron R. Folsom,Eric J.G. Sijbrands,James S. Pankow,Paul Elliott,John F. Keaney,John F. Keaney,Wei Sun,Antti-Pekka Sarin,João D. Fontes,João D. Fontes,Sunita Badola,Brad C. Astor,Albert Hofman,Anneli Pouta,Karl Werdan,Karin Halina Greiser,Karin Halina Greiser,Oliver Kuss,Henriette E. Meyer zu Schwabedissen,Joachim Thiery,Yalda Jamshidi,Yalda Jamshidi,Ilja M. Nolte,Nicole Soranzo,Tim D. Spector,Henry Völzke,Alex Parker,Thor Aspelund,David W. Bates,Lauren Young,Kim Tsui,David S. Siscovick,Xiuqing Guo,Jerome I. Rotter,Manuela Uda,David Schlessinger,Igor Rudan,Igor Rudan,Andrew A. Hicks,Brenda W.J.H. Penninx,Barbara Thorand,Christian Gieger,Joe Coresh,Gonneke Willemsen,Tamara B. Harris,André G. Uitterlinden,Marjo-Riitta Järvelin,Kenneth Rice,Dörte Radke,Veikko Salomaa,Ko Willems van Dijk,Eric Boerwinkle,Ramachandran S. Vasan,Luigi Ferrucci,Quince Gibson,Stefania Bandinelli,Harold Snieder,Dorret I. Boomsma,Xiangjun Xiao,Harry Campbell,Caroline Hayward,Peter P. Pramstaller,Cornelia M. van Duijn,Leena Peltonen,Bruce M. Psaty,Vilmundur Gudnason,Paul M. Ridker,Georg Homuth,Wolfgang Koenig,Christie M. Ballantyne,Jacqueline C.M. Witteman,Emelia J. Benjamin,Markus Perola,Daniel I. Chasman +121 more
TL;DR: A genome-wide association analysis of CRP identified 18 loci that were associated with CRP levels and highlighted immune response and metabolic regulatory pathways involved in the regulation of chronic inflammation.