Karthik Urs

TL;DR: It is demonstrated that a single, complex gene locus in Bacteroides ovatus confers XyG catabolism in this common colonic symbiont, and the metabolism of even highly abundant components of dietary fibre may be mediated by niche species.

TL;DR: Genomic comparison with B. thetaiotaomicron in conjunction with cell culture studies show that a cohort of highly successful members of the microbiota has evolved to consume sterically-restricted yeast glycans, an adaptation that may reflect the incorporation of eukaryotic microorganisms into the human diet.

TL;DR: Investigating the responses of Bacteroides thetaiotaomicron, a common human intestinal bacterium that metabolizes more than a dozen different polysaccharides, reveals new aspects of how individual bacteria partition to “preferred niches” in the complex gut ecosystem, which has important and immediate implications for understanding and predicting the behavioral dynamics of this community.

TL;DR: Molecular insight is provided into the function of an archetypal MLG utilization locus (MLGUL) through a combination of biochemistry, enzymology, structural biology, and microbiology that underscores the importance of gut microbial metabolism of MLG as a common cereal polysaccharide.

TL;DR: This corrects the article to show that the method used to derive the H2O2 “spatially aggregating force” is based on a two-step process, not a single step, like in the previous version of this paper.