K
Kazuki Nakajima
Researcher at Fujita Health University
Publications - 49
Citations - 1149
Kazuki Nakajima is an academic researcher from Fujita Health University. The author has contributed to research in topics: Glycan & Glycosylation. The author has an hindex of 21, co-authored 47 publications receiving 958 citations. Previous affiliations of Kazuki Nakajima include National Institute of Advanced Industrial Science and Technology & RIKEN Brain Science Institute.
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Journal ArticleDOI
Structural Characterization of Pyridylaminated Oligosaccharides Derived from Neutral Glycosphingolipids by High-Sensitivity Capillary Electrophoresis–Mass Spectrometry
Emi Ito,Kazuki Nakajima,Hiroaki Waki,Kozo Miseki,Takashi Shimada,Taka-Aki Sato,Kazuaki Kakehi,Minoru Suzuki,Naoyuki Taniguchi,Akemi Suzuki +9 more
TL;DR: The developed CE-MS system is a powerful method for the structural characterization of glycosphingolipids extracted from very small amounts of biological materials and could be extended to the structural characterize of oligosaccharides derived from glycoproteins.
Journal ArticleDOI
Analysis of O-glycoforms of the IgA1 hinge region by sequential deglycosylation.
Yukako Ohyama,Hisateru Yamaguchi,Kazuki Nakajima,Tomohiro Mizuno,Yukihiro Fukamachi,Yasuto Yokoi,Naotake Tsuboi,Daijo Inaguma,Midori Hasegawa,Matthew B. Renfrow,Jan Novak,Yukio Yuzawa,Kazuo Takahashi,Kazuo Takahashi +13 more
TL;DR: An automated quantitative analysis of the HR O-glycopeptide profiles with sequential deglycosylation will enable identification of pathogenic IgA1 HR o-glycoforms in IgAN.
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Structural characterization of multibranched oligosaccharides from seal milk by a combination of off-line high-performance liquid chromatography-matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry and sequential exoglycosidase digestion
Mitsuhiro Kinoshita,Hiroko Ohta,Kanata Higaki,Yoko Kojima,Tadasu Urashima,Kazuki Nakajima,Minoru Suzuki,Kit M. Kovacs,Christian Lydersen,Takao Hayakawa,Kazuaki Kakehi +10 more
TL;DR: Analysis of milk samples of bearded and hooded seals revealed that oligosaccharides from both seal species were composed from lacto-N-neohexaose as the common core structure, and most of them contained Fucalpha1-2 residues at the nonreducing ends.
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Glycometabolic Regulation of the Biogenesis of Small Extracellular Vesicles.
Yoichiro Harada,Kazuki Nakajima,Takehiro Suzuki,Tomoko Fukushige,Kiyotaka Kondo,Junichi Seino,Yuki Ohkawa,Tadashi Suzuki,Hiromasa Inoue,Takuro Kanekura,Naoshi Dohmae,Naoyuki Taniguchi,Ikuro Maruyama +12 more
TL;DR: It is suggested that N-glycosylation facilitates sEV biogenesis through cargo protein sorting through cargoprotein sorting at specific sites of the hepatocyte growth factor receptor and facilitates its sorting into vesicles.
Journal ArticleDOI
Separation and analysis of mono-glucosylated lipids in brain and skin by hydrophilic interaction chromatography based on carbohydrate and lipid moiety
Kazuki Nakajima,Hisako Akiyama,Kaori Tanaka,Ayako Kohyama-Koganeya,Peter Greimel,Yoshio Hirabayashi +5 more
TL;DR: The ZIC-HILIC-based approach is a valuable tool for characterizing the structural diversity of mono-glucosylated lipids in biological material and for quantifying these important lipids.