K
Kazuyoshi Kobayashi
Researcher at Nagoya University
Publications - 239
Citations - 3185
Kazuyoshi Kobayashi is an academic researcher from Nagoya University. The author has contributed to research in topics: Myelopathy & Medicine. The author has an hindex of 19, co-authored 225 publications receiving 2083 citations. Previous affiliations of Kazuyoshi Kobayashi include University of Tsukuba.
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Journal ArticleDOI
Minocycline selectively inhibits M1 polarization of microglia
Kazuyoshi Kobayashi,Shiro Imagama,Tomohiro Ohgomori,Kenichi Hirano,Kenji Uchimura,Kazuma Sakamoto,Akihiro Hirakawa,Hideyuki Takeuchi,Akio Suzumura,Naoki Ishiguro,Kenji Kadomatsu +10 more
TL;DR: It is indicated that minocycline selectively inhibits the microglia polarization to a proinflammatory state, and provides a basis for understanding pathogeneses of many diseases accompanied by microglial activation.
Journal ArticleDOI
Epidemiological trends in spine surgery over 10 years in a multicenter database
TL;DR: This large-scale study provides indicators for planning the future development of spine surgery and for treatment of spinal diseases in daily practice, with a focus on the effects of the superaging society on the characteristics and trends of spinal surgeries.
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Staged decrease of physical ability on the locomotive syndrome risk test is related to neuropathic pain, nociceptive pain, shoulder complaints, and quality of life in middle-aged and elderly people – The utility of the locomotive syndrome risk test
Shiro Imagama,Yukiharu Hasegawa,Kei Ando,Kazuyoshi Kobayashi,Tetsuro Hida,Kenyu Ito,Mikito Tsushima,Yoshihiro Nishida,Naoki Ishiguro +8 more
TL;DR: Shoulder complaint, neuropathic pain, nociceptive pain, shoulder complaints, and QOL differed significantly among all three groups and worsened with decline in mobility on the LS risk test.
Journal ArticleDOI
Complications Associated With Spine Surgery in Patients Aged 80 Years or Older: Japan Association of Spine Surgeons with Ambition (JASA) Multicenter Study.
Kazuyoshi Kobayashi,Shiro Imagama,Kei Ando,Naoki Ishiguro,Masaomi Yamashita,Yawara Eguchi,Morio Matsumoto,Ken Ishii,Tomohiro Hikata,Shoji Seki,Hidetomi Terai,Akinobu Suzuki,Koji Tamai,Masaaki Aramomi,Tetsuhiro Ishikawa,Atsushi Kimura,Hirokazu Inoue,Gen Inoue,Masayuki Miyagi,Wataru Saito,Kei Yamada,Michio Hongo,Hirosuke Nishimura,Hidekazu Suzuki,Atsushi Nakano,Kazuyuki Watanabe,Hirotaka Chikuda,Junichi Ohya,Yasuchika Aoki,Masayuki Shimizu,Toshimasa Futatsugi,Keijiro Mukaiyama,Masaichi Hasegawa,Katsuhito Kiyasu,Haku Iizuka,Yoichi Iizuka,Ryoichi Kobayashi,Kotaro Nishida,Kenichiro Kakutani,Hideaki Nakajima,Hideki Murakami,Satoru Demura,Satoshi Kato,Katsuhito Yoshioka,Takashi Namikawa,Kei Watanabe,Kazuyoshi Nakanishi,Yukihiro Nakagawa,Mitsunori Yoshimoto,Hiroyasu Fujiwara,Norihiro Nishida,Yasuaki Imajo,Masashi Yamazaki,Masataka Sakane,Tetsuya Abe,Kengo Fujii,Takashi Kaito,Takeo Furuya,Sumihisa Orita,Seiji Ohtori +59 more
TL;DR: Elderly patients aged 80 years or older with comorbidities are at higher risk for complications, and careful decisions are required with regard to the surgical indication and procedure in elderly patients.
Journal ArticleDOI
Alert Timing and Corresponding Intervention With Intraoperative Spinal Cord Monitoring for High-Risk Spinal Surgery.
Go Yoshida,Muneharu Ando,Shiro Imagama,Shigenori Kawabata,Kei Yamada,Tsukasa Kanchiku,Yasushi Fujiwara,Nobuaki Tadokoro,Masahito Takahashi,Kanichiro Wada,Naoya Yamamoto,Sho Kobayashi,Hiroki Ushirozako,Kazuyoshi Kobayashi,Akimasa Yasuda,Toshikazu Tani,Yukihiro Matsuyama +16 more
TL;DR: Although the rescue ratios for t-OPLL and IMSCT were relatively low, appropriate intervention immediately after an IONM alert may prevent neural damage even in high-risk spinal surgeries, according to a prospective multicenter study.