K
Klaus M. Hahn
Researcher at University of North Carolina at Chapel Hill
Publications - 215
Citations - 16976
Klaus M. Hahn is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: RHOA & Proto-oncogene tyrosine-protein kinase Src. The author has an hindex of 61, co-authored 210 publications receiving 15343 citations. Previous affiliations of Klaus M. Hahn include University of California, Berkeley & University of California, San Diego.
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Journal ArticleDOI
Geological Mapping and Characterization of Possible Primary Input Materials for the Mineral Sequestration of Carbon Dioxide in Europe
Dario Kremer,Simon Etzold,Judith Boldt,Peter Blaum,Klaus M. Hahn,Hermann Wotruba,Rainer Telle +6 more
TL;DR: In this paper, the authors investigated the possible mineral input materials for the process of mineral sequestration through the carbonation of magnesium or calcium silicates under high pressure and high temperatures in an autoclave.
Journal ArticleDOI
PLEKHG3 enhances polarized cell migration by activating actin filaments at the cell front
Trang T. T. Nguyen,Wei Sun Park,Byung Ouk Park,Cha Yeon Kim,Yohan Oh,Jin Man Kim,Hana Choi,Taeyoon Kyung,Cheol-Hee Kim,Gabsang Lee,Klaus M. Hahn,Tobias Meyer,Won Do Heo +12 more
TL;DR: It is shown that the pleckstrin homology and RhoGEF domain containing G3 (PLEKHG3) is a PI3K-regulated Rho guanine nucleotide exchange factor (Rho GEF) for Rac1 and Cdc42 that selectively binds to newly polymerized actin at the leading edge of migrating fibroblasts.
Journal ArticleDOI
Optogenetic control of cofilin and αTAT in living cells using Z-lock.
Orrin J. Stone,Neha Pankow,Bei Liu,Ved P. Sharma,Robert J. Eddy,Hui Wang,Andrew T. Putz,Frank D. Teets,Brian Kuhlman,John S. Condeelis,Klaus M. Hahn +10 more
TL;DR: Z-lock, an optogenetic approach for reversible, light-controlled steric inhibition of protein active sites, relies on a steric block placed over important regions of the target protein that can be released reversibly.
Journal ArticleDOI
p190RhoGAP negatively regulates Rho activity at the cleavage furrow of mitotic cells.
TL;DR: It is suggested that p190 regulates cytokinesis through modulation of RhoGTP levels, thereby affecting CF specification site selection and subsequent ring contraction.
Journal ArticleDOI
Combined Atomic Force Microscope and Volumetric Light Sheet System for Correlative Force and Fluorescence Mechanobiology Studies.
Evan F. Nelsen,Chad M. Hobson,Megan E. Kern,Joe Ping Lin Hsiao,Edward Timothy O'Brien,Takashi Watanabe,Brett M Condon,Michael Boyce,Sergio Grinstein,Klaus M. Hahn,Michael R. Falvo,Richard Superfine +11 more
TL;DR: An instrument that combines an open-top, single-objective light sheet fluorescence microscope with an atomic force microscope, providing simultaneous volumetric imaging with high spatiotemporal resolution and high dynamic range force capability is presented.