L. Calabrese

TL;DR: Given the high prevalence of chronic viral infections in patients who are candidates for anti-TNF therapy and the potential for these agents in the treatment of Chronic viral illness, additional studies are urgently needed to assess the risks and benefits of such therapy in these populations.

TL;DR: Limitations in current classification criteria and definitions for vasculitis have been identified and suggestions provided for improvement and it is proposed that, in combination with the updated evidence, these should form the basis of future attempts to develop and validate revised criteria and definition of vasulitis.

TL;DR: In this article, a systematic literature review was undertaken looking to address these deficiencies and produce 'points to consider' in accordance with standardised European League Against Rheumatism (EULAR) operating procedures.

TL;DR: The consensus group developed a working definition for OIs as ‘indicator’ infections, defined as specific pathogens or presentations of pathogens that ’indicate’ the likelihood of an alteration in host immunity in the setting of biologic therapy.

TL;DR: While SIE rates were higher for CZP than for placebo in RCT, the rate decreased with continued exposure to CZp, consistent with data previously reported for CzP and other tumour necrosis factor inhibitors.