L
Leondios G. Kostrikis
Researcher at University of Cyprus
Publications - 86
Citations - 7580
Leondios G. Kostrikis is an academic researcher from University of Cyprus. The author has contributed to research in topics: Population & Genotype. The author has an hindex of 39, co-authored 82 publications receiving 7154 citations. Previous affiliations of Leondios G. Kostrikis include Aaron Diamond AIDS Research Center & National and Kapodistrian University of Athens.
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Journal ArticleDOI
Cellular HIV-1 DNA load predicts HIV-RNA rebound and the outcome of highly active antiretroviral therapy.
Angelos Hatzakis,Giota Touloumi,Nikos Pantazis,Cleo Anastassopoulou,Olga Katsarou,Anastasia Karafoulidou,James J. Goedert,Leondios G. Kostrikis +7 more
TL;DR: Low cellular HIV-1 DNA load is a marker of sustained virological response in patients with initial VR and it can reliably predict the long-term success of HAART.
Journal ArticleDOI
The global spread of HIV-1 subtype B epidemic
Gkikas Magiorkinis,Konstantinos Angelis,Ioannis Mamais,Aris Katzourakis,Angelos Hatzakis,Jan Albert,Glenn Lawyer,Osamah Hamouda,Daniel Struck,Jurgen Vercauteren,Annemarie M. J. Wensing,Ivailo Alexiev,Birgitta Åsjö,Claudia Balotta,Perpétua Gomes,Ricardo Jorge Camacho,Suzie Coughlan,Algirdas Griskevicius,Zehava Grossman,Anders Horban,Leondios G. Kostrikis,Snjezana J Lepej,Kirsi Liitsola,Marek Linka,Claus Nielsen,Dan Otelea,Roger Paredes,Mario Poljak,Elizabeth Puchhammer-Stöckl,Jean-Claude Schmit,Anders Sönnerborg,Danica Staneková,Maja Stanojevic,Dora C. Stylianou,Charles A. Boucher,Georgios K. Nikolopoulos,Tetyana I. Vasylyeva,Samuel R. Friedman,David A. M. C. van de Vijver,Gioacchino Angarano,Marie-Laure Chaix,Andrea De Luca,Klaus Korn,Clive Loveday,Vincent Soriano,Sabine Yerly,Mauricio Zazzi,Anne-Mieke Vandamme,Dimitrios Paraskevis +48 more
TL;DR: It is shown that subtype B travelled from North America to Western Europe in different occasions, while Central/Eastern Europe remained isolated for the most part of the early epidemic, which supports the argument that epidemic control policies should be global and incorporate political and socioeconomic factors.
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CXCR4 mediates entry and productive infection of syncytia-inducing (X4) HIV-1 strains in primary macrophages.
TL;DR: It is demonstrated that CXCR4 is the main HIV-1 SI coreceptor in human primary macrophages and underline the importance of the macrophage as a long-living viral reservoir for HIV- 1.
Journal ArticleDOI
Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe
Dineke Frentz,David A. M. C. van de Vijver,Ana B. Abecasis,Jan Albert,Jan Albert,Osamah Hamouda,Louise B. Jørgensen,Claudia Kücherer,Daniel Struck,Jean-Claude Schmit,Jurgen Vercauteren,Birgitta Åsjö,Claudia Balotta,Danail Beshkov,Ricardo Jorge Camacho,Bonaventura Clotet,Suzie Coughlan,Algirdas Griskevicius,Zehava Grossman,Andrzej Horban,Tatjana Kolupajeva,Klaus Korn,Leondios G. Kostrikis,Kirsi Liitsola,Marek Linka,Claus Nielsen,Dan Otelea,Dimitrios Paraskevis,Roger Paredes,Mario Poljak,Elisabeth Puchhammer-Stockl,Anders Sönnerborg,Anders Sönnerborg,Danica Staneková,Maja Stanojevic,Eric Van Wijngaerden,Annemarie M. J. Wensing,Charles A. Boucher +37 more
TL;DR: During the years 2002 to 2007 transmitted resistance to NNRTI has doubled to 4% in Europe, andylogenetic analysis showed that these temporal changes could not be explained by large clusters of TDRM.
Journal ArticleDOI
CCR5 Promoter Polymorphisms in a Kenyan Perinatal Human Immunodeficiency Virus Type 1 Cohort: Association with Increased 2-Year Maternal Mortality
Grace C. John,Thomas G. Bird,Julie Overbaugh,Ruth Nduati,Dorothy Mbori-Ngacha,Tim Rostron,Tao Dong,Leondios G. Kostrikis,Barbra A. Richardson,Sarah Rowland-Jones +9 more
TL;DR: In this article, the authors investigated the effect of maternal CCR5 promoter polymorphisms on maternal plasma viremia, shedding of cervical and vaginal HIV-1 infected cells, and 2-year survival in a perinatal transmission cohort in Nairobi, Kenya.