L
Lily C. Wang
Researcher at Cornell University
Publications - 17
Citations - 604
Lily C. Wang is an academic researcher from Cornell University. The author has contributed to research in topics: Cancer & PTEN. The author has an hindex of 10, co-authored 17 publications receiving 531 citations. Previous affiliations of Lily C. Wang include Columbia University & International Agency for Research on Cancer.
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Journal ArticleDOI
Cdc45 Is a Critical Effector of Myc-Dependent DNA Replication Stress
TL;DR: It is found that overexpression of c-Myc alters the spatiotemporal program of replication initiation by increasing the density of early-replicating origins and results in elevated replication-fork stalling or collapse and subsequent DNA damage.
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Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity.
Akash Patnaik,Kenneth D. Swanson,Eva Csizmadia,Aniruddh Solanki,Aniruddh Solanki,Natalie Landon-Brace,Natalie Landon-Brace,Marina P. Gehring,Marina P. Gehring,Katja Helenius,Brian Olson,Athalia Rachel Pyzer,Lily C. Wang,Olivier Elemento,Jesse Novak,Thomas B. Thornley,John M. Asara,Laleh Montaser,Joshua J. Timmons,Todd M. Morgan,Yugang Wang,Elena Levantini,Elena Levantini,Elena Levantini,John G. Clohessy,Kathleen Kelly,Pier Paolo Pandolfi,Jacalyn Rosenblatt,David Avigan,Huihui Ye,Jeffrey M. Karp,Jeffrey M. Karp,Sabina Signoretti,Steven P. Balk,Lewis C. Cantley +34 more
TL;DR: This study is the first to demonstrate that a tyrosine kinase inhibitor can activate neutrophil-mediated antitumor innate immunity, resulting in invasive cancer clearance, in mice.
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Checkpoint signaling from a single DNA interstrand crosslink
Merav Ben-Yehoyada,Lily C. Wang,Ivan D. Kozekov,Carmelo J. Rizzo,Max E. Gottesman,Jean Gautier +5 more
TL;DR: This work demonstrates that ICLs trigger a checkpoint response independently of origin-initiated DNA replication and uncoupling of DNA polymerase and DNA helicase, and suggests that cell sensitivity to crosslinking agents results from both checkpoint and DNA repair defects.
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Fanconi anemia proteins stabilize replication forks.
TL;DR: Using Xenopus cell-free extracts, it is shown that FANCL depletion results in defective DNA replication restart following treatment with camptothecin, a drug that results in DSBs during DNA replication.
Journal ArticleDOI
Trends in Mesh Use for Pelvic Organ Prolapse Repair From the Medicare Database
Lily C. Wang,Jim C. Hu,Melissa A. Laudano,Wesley Davison,Michael Schulster,Fujun Zhao,Bilal Chughtai,Richard K. Lee +7 more
TL;DR: The use of mesh use for pelvic organ prolapse (POP)-related reconstruction procedures increased significantly until 2008, after which it plateaued following the Food and Drug Administration warning regarding mesh-related complications.