L
Ling Fang
Researcher at Chinese Center for Disease Control and Prevention
Publications - 16
Citations - 673
Ling Fang is an academic researcher from Chinese Center for Disease Control and Prevention. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 2 publications receiving 614 citations. Previous affiliations of Ling Fang include Centers for Disease Control and Prevention.
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Journal ArticleDOI
Molecular Evolution of the SARS Coronavirus, during the Course of the SARS Epidemic in China
Jian Feng He,Guo Wen Peng,Jun Min,De Wen Yu,Wen Jia Liang,Shuyi Zhang,Rui Heng Xu,Huan Ying Zheng,Xin Wei Wu,Jun Xu,Zhan Hui Wang,Ling Fang,Xin Zhang,Hui Li,Xin Ge Yan,Jiahai Lu,Zhihong Hu,Ji Cheng Huang,Zhuo Yue Wan,Jin Lin Hou,Jin Yan Lin,Huai Dong Song,Shengyue Wang,Xiang Jun Zhou,Guo Wei Zhang,Bo Wei Gu,Huajun Zheng,Xiang Lin Zhang,Mei He,Kui Zheng,Bo Fei Wang,Gang Fu,Xiao Ning Wang,Sai Juan Chen,Zhu Chen,Zhu Chen,Pei Hao,Hua Tang,Shuang Xi Ren,Yang Zhong,Zong Ming Guo,Qi Liu,You Gang Miao,Xiangyin Kong,Wei Zhong He,Yixue Li,Chung-I Wu,Guoping Zhao,Rossa W.K. Chiu,Stephen S.C. Chim,Yu K. Tong,Paul K.S. Chan,John S. Tam,Y.M. Dennis Lo +53 more
TL;DR: The spike protein showed the strongest initial responses to positive selection pressures, followed by subsequent purifying selection and eventual stabilization, and major deletions were observed in the Orf8 region of the genome at the start and the end of the epidemic.
Journal Article
Humoral immune responses in rabbits induced by an experimental inactivated severe acute respiratory syndrome coronavirus vaccine prepared from F69 strain.
Chuan-hai Zhang,Zhongmin Guo,Huan-Ying Zheng,Jiahai Lu,Wang Yifei,Xin-Ge Yan,Yong Zhao,Xiong-Wei Du,Xin Zhang,Ling Fang,Wen-Hua Ling,Shu-Yuan Qi,Xin-Bing Yu,Nanshan Zhong +13 more
TL;DR: The inactivated SARS-CoV vaccine made from F69 strain owns strong immunogenicity, and the cross neutralization response between the two different SARS -CoV strains gives a hint of the similar neutralizing epitopes, which provide stable bases for the development of inactivatedSARS- CoV vaccines.
Journal ArticleDOI
Cost-effectiveness analysis of sugemalimab vs. chemotherapy as first-line treatment of metastatic nonsquamous non-small cell lung cancer
TL;DR: Sugemalimab combination therapy is not economically advantageous for the first-line management of metastatic non-squamous NSCLC, according to the Chinese healthcare system.
Journal ArticleDOI
Untangling an AGS Outbreak Caused by the Recombinant GII.12[P16] Norovirus With Nanopore Sequencing
Qianlin Xiong,Huimin Jiang,Zhe Liu,Jinju Peng,Jing Sun,Ling Fang,Caixia Li,Ming Qiu,Xing Zhang,Jing Lu +9 more
TL;DR: The sequencing results indicated the outbreak was likely caused by an emerging recombinant GII.12[P16] virus, which was only identified in the United States and Canada in 2017–2018, and highlighted the importance of real-time sequencing in emerging pathogens’ surveillance.
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Taohong siwu decoction attenuates AIM2 and NLRC4 inflammasomes by ameliorates deoxyribonucleic acid damage after ischemic stroke
Ni Wang,Furui Chu,Liyuan Zhang,Chan Kok Fei,Chao Yu,Sujun Xue,Yong-Zhong Wang,Ling Fang,Daiyin Peng,Xianchun Duan,Weidong Chen +10 more
TL;DR: The data suggest that THSWD can reduced DNA damage after stroke as well as the inflammatory response caused by the damage.