Lingshuang Ren

TL;DR: The authors found that most of the secondary transmissions could be traced back to a minority of infected individuals, and well over half of transmission occurred in the presymptomatic phase, which could help in the design of infection control policies that have the potential to minimize both virus transmission and economic strain.

TL;DR: Based on individual records of 1178 potential SARS-CoV-2 infectors and their 15,648 contacts in Hunan, China, the authors estimated key transmission parameters.

TL;DR: Modelling results indicate that achieving SARS-CoV-2 control would require the synergistic efforts of case isolation, contact quarantine, and population-level physical distancing measures, owing to the particular transmission kinetics of this virus.

TL;DR: These findings support the contribution of children to transmission and the importance of pre-symptomatic transmission, in turn highlighting the need for large-scale testing, contact tracing activities, and the use of personnel protective equipment during the COVID-19 pandemic.

TL;DR: Two reference samples for NGS technologies: a human triple-negative breast cancer cell line and a matched normal cell line are characterized to facilitate assay development, qualification, validation, and proficiency testing and “truth sets” are defined using evidence from 21 repeats of WGS runs with coverages ranging from 50X to 100X.