M
Manish D. Sinha
Researcher at Boston Children's Hospital
Publications - 186
Citations - 3943
Manish D. Sinha is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Population & Kidney disease. The author has an hindex of 27, co-authored 155 publications receiving 2858 citations. Previous affiliations of Manish D. Sinha include Blackpool Victoria Hospital & King's College London.
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Journal ArticleDOI
2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents
Empar Lurbe,Enrico Agabiti-Rosei,J. Kennedy Cruickshank,Anna F. Dominiczak,Serap Erdine,Asle Hirth,Cecilia Invitti,Mieczysław Litwin,Giuseppe Mancia,Dénes Páll,Wolfgang Rascher,Josep Redon,Franz Schaefer,Tomáš Seeman,Manish D. Sinha,Stella Stabouli,Nicholas J. A. Webb,Elke Wühl,Alberto Zanchetti +18 more
TL;DR: The recommendations of the present document represent the best clinical wisdom upon which physicians, nurses and families should base their decisions and should encourage public policy makers to develop a global effort to improve identification and treatment of high blood pressure among children and adolescents.
Journal ArticleDOI
Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management
Agnieszka Bierzynska,Hugh J. McCarthy,Katrina Soderquest,Ethan S Sen,Elizabeth Colby,Wen Y. Ding,Marwa M. Nabhan,Larissa Kerecuk,Shivram Hegde,David Hughes,Stephen D. Marks,Sally Feather,Caroline Jones,Nicholas J. A. Webb,Milos Ognjanovic,Martin Christian,Rodney D. Gilbert,Manish D. Sinha,Graham M. Lord,Michael A. Simpson,Ania Koziell,Gavin I. Welsh,Moin A. Saleem +22 more
TL;DR: Deep phenotyping combined with whole exome sequencing is an effective tool for early identification of SRNS etiology, yielding an evidence-based algorithm for clinical management.
Journal ArticleDOI
Disease activity, severity, and damage in the UK juvenile‐onset systemic lupus erythematosus cohort
L Watson,Valentina Leone,Clarissa Pilkington,Kjell Tullus,Satyapal Rangaraj,Janet E. McDonagh,Janet Gardner-Medwin,Nick Wilkinson,Phil Riley,Jane Tizard,Kate Armon,Manish D. Sinha,Yiannis Ioannou,Neil Archer,Kathryn Bailey,Joyce Davidson,Eileen Baildam,Gavin Cleary,Liza J McCann,Michael W. Beresford +19 more
TL;DR: The data on these patients from the UK JSLE Cohort Study indicate that severe organ involvement and significant disease activity are primary characteristics in children with juvenile SLE.
Journal ArticleDOI
Accuracy of Cuff-Measured Blood Pressure: Systematic Reviews and Meta-Analyses
Dean S. Picone,Martin G. Schultz,Petr Otahal,Svend Aakhus,Ahmed M. Al-Jumaily,J. Andrew Black,J. Andrew Black,Willem Jan W. Bos,John C. Chambers,Chen Huan Chen,Hao Min Cheng,Antoine Cremer,Justin E. Davies,Nathan Dwyer,Nathan Dwyer,Brian Gould,Alun D. Hughes,Peter S. Lacy,Esben Laugesen,Fuyou Liang,Roman Melamed,Sandy Muecke,Nobuyuki Ohte,Sho Okada,Stefano Omboni,Christian Ott,Xiaoqing Peng,Telmo Pereira,Giacomo Pucci,Ronak Rajani,Philip Roberts-Thomson,Philip Roberts-Thomson,Niklas B. Rossen,Daisuke Sueta,Manish D. Sinha,Roland E. Schmieder,Harold Smulyan,Velandai Srikanth,Velandai Srikanth,Ralph A.H. Stewart,George A. Stouffer,Kenji Takazawa,Ji-Guang Wang,Berend E. Westerhof,Franz Weber,Thomas C. Weber,Bryan Williams,Hirotsugu Yamada,Eiichiro Yamamoto,James E. Sharman +49 more
TL;DR: Cuff BP has variable accuracy for measuring either brachial or aortic intra-arterial BP, and this adversely influences correct BP classification, indicating that stronger accuracy standards for BP devices may improve cardiovascular risk management.
Journal ArticleDOI
Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.
Daniela A. Braun,Jia Rao,Géraldine Mollet,Géraldine Mollet,David Schapiro,Marie Claire Daugeron,Weizhen Tan,Olivier Gribouval,Olivier Gribouval,Olivia Boyer,Olivia Boyer,Patrick Revy,Patrick Revy,Tilman Jobst-Schwan,Johanna Magdalena Schmidt,Jennifer A. Lawson,Denny Schanze,Shazia Ashraf,Jeremy F.P. Ullmann,Charlotte A. Hoogstraten,Nathalie Boddaert,Nathalie Boddaert,Bruno Collinet,Bruno Collinet,Gaëlle H. Martin,Gaëlle H. Martin,Dominique Liger,Svjetlana Lovric,Mónica Furlano,Mónica Furlano,Mónica Furlano,I. Chiara Guerrera,Oraly Sanchez-Ferras,Jennifer Hu,Anne Claire Boschat,Sylvia Sanquer,Björn Menten,Sarah Vergult,Nina De Rocker,Merlin Airik,Tobias Hermle,Shirlee Shril,Eugen Widmeier,Eugen Widmeier,Heon Yung Gee,Heon Yung Gee,Won-Il Choi,Carolin E. Sadowski,Werner L. Pabst,Jillian K. Warejko,Ankana Daga,Tamara Basta,Verena Matejas,Karin Scharmann,Karin Scharmann,Sandra D. Kienast,Sandra D. Kienast,Babak Behnam,Babak Behnam,Brendan Beeson,Amber Begtrup,Malcolm Bruce,Gaik Siew Ch’ng,Shuan-Pei Lin,Shuan-Pei Lin,Jui Hsing Chang,Chao Huei Chen,Megan T. Cho,Patrick M. Gaffney,Patrick E. Gipson,Chyong Hsin Hsu,Jameela A. Kari,Yu Yuan Ke,Cathy Kiraly-Borri,Wai Ming Lai,Emmanuelle Lemyre,Rebecca O. Littlejohn,Amira Masri,Mastaneh Moghtaderi,Kazuyuki Nakamura,Fatih Ozaltin,Marleen Praet,Chitra Prasad,Agnieszka Prytuła,Elizabeth Roeder,Patrick Rump,Rhonda E. Schnur,Takashi Shiihara,Manish D. Sinha,Neveen A. Soliman,Kenza Soulami,David A. Sweetser,Wen Hui Tsai,Jeng Daw Tsai,Jeng Daw Tsai,Jeng Daw Tsai,Rezan Topaloglu,Udo Vester,David Viskochil,Nithiwat Vatanavicharn,Jessica L. Waxler,Klaas J. Wierenga,Matthias T.F. Wolf,Sik Nin Wong,Sebastian A. Leidel,Sebastian A. Leidel,Gessica Truglio,Peter C. Dedon,Peter C. Dedon,Annapurna Poduri,Shrikant Mane,Richard P. Lifton,Richard P. Lifton,Maxime Bouchard,Peter Kannu,David Chitayat,Daniella Magen,Bert Callewaert,Herman van Tilbeurgh,Martin Zenker,Corinne Antignac,Corinne Antignac,Friedhelm Hildebrandt +122 more
TL;DR: Four new monogenic causes of GAMOS are identified, a link between KEOPS function and human disease is described, and potential pathogenic mechanisms are delineated.