L
Luciana C. C. Leite
Researcher at Instituto Butantan
Publications - 142
Citations - 5878
Luciana C. C. Leite is an academic researcher from Instituto Butantan. The author has contributed to research in topics: Schistosoma mansoni & Antigen. The author has an hindex of 37, co-authored 133 publications receiving 5377 citations. Previous affiliations of Luciana C. C. Leite include University of São Paulo & University of Ottawa.
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Journal ArticleDOI
The genome sequence of the plant pathogen Xylella fastidiosa
Andrew J. G. Simpson,Fernando C. Reinach,Paulo Arruda,F. A. Abreu,Marcio Luis Acencio,R. Alvarenga,Lucia Maria Carareto Alves,Jorge E. Araya,Gilson S. Baia,C. S. Baptista,Mario H. Barros,Eric D. Bonaccorsi,Silvana Bordin,Joseph M. Bové,Marcelo R.S. Briones,M. R.P. Bueno,Anamaria A. Camargo,Luis Eduardo Aranha Camargo,Dirce Maria Carraro,Helaine Carrer,N. B. Colauto,Carlos Augusto Colombo,Fernando Ferreira Costa,M. C. R. Costa,Claudio M. Costa-Neto,Luiz Lehmann Coutinho,M. Cristofani,Emmanuel Dias-Neto,C. Docena,Hamza El-Dorry,Agda Paula Facincani,Ari J. S. Ferreira,V. C.A. Ferreira,Jesus Aparecido Ferro,Jane Silveira Fraga,Suzelei C. França,Marília Caixeta Franco,Marcus Frohme,Luiz Roberto Furlan,M. Garnier,Gustavo H. Goldman,Maria Helena S. Goldman,Suely Lopes Gomes,Arthur Gruber,Paulo L. Ho,Joerg Hoheisel,M.L. Junqueira,Edson L. Kemper,João Paulo Kitajima,José Eduardo Krieger,Eiko E. Kuramae,F. Laigret,Marcio Rodrigues Lambais,Luciana C. C. Leite,Eliana Gertrudes de Macedo Lemos,Manoel Victor Franco Lemos,Silvio A. Lopes,Catalina Romero Lopes,J. A. Machado,Marco Antonio Machado,Alda Maria Backx Noronha Madeira,Humberto Maciel França Madeira,Humberto Maciel França Madeira,Celso Luis Marino,Marilis V. Marques,Elizabeth A. L. Martins,E. M.F. Martins,Adriana Yamaguti Matsukuma,Carlos Frederico Martins Menck,E. C. Miracca,Cristina Yumi Miyaki,Claudia Barros Monteiro-Vitorello,D. H. Moon,Maria Aparecida Nagai,Ana L. T. O. Nascimento,Luis Eduardo Soares Netto,A. Nhani,Francisco G. Nobrega,Francisco G. Nobrega,Luiz R. Nunes,Marcos Antonio de Oliveira,M. C. de Oliveira,R. C. de Oliveira,Darío Abel Palmieri,A. Paris,B. R. Peixoto,Gonçalo A.G. Pereira,H. A. Pereira,João Bosco Pesquero,Ronaldo Bento Quaggio,Patrícia G. Roberto,Vanderlei Rodrigues,Artur J.M. Rosa,V. E. de Rosa,R. G. de Sá,Roberto Vicente Santelli,H. E. Sawasaki,A.C.R. da Silva,A M da Silva,F. R. da Silva,Wilson A. Silva,J. F. da Silveira,M. L.Z. Silvestri,Walter José Siqueira,A. A. de Souza,A. P. de Souza,M. F. Terenzi,Daniela Truffi,Siu Mui Tsai,M. H. Tsuhako,Homero Vallada,M. A. Van Sluys,Sergio Verjovski-Almeida,André Luiz Vettore,Marco Antônio Zago,Mayana Zatz,João Meidanis,João C. Setubal +117 more
TL;DR: The complete genome sequence of X. fastidiosa clone 9a5c is reported, providing direct evidence of phage-mediated horizontal gene transfer and indicating that the molecular basis for bacterial pathogenicity is both conserved and independent of host.
Journal ArticleDOI
Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni
Sergio Verjovski-Almeida,Ricardo DeMarco,Elizabeth A. L. Martins,Pedro Edson Moreira Guimarães,Elida B. Ojopi,Apuã C.M. Paquola,João Paulo Piazza,Milton Y. Nishiyama,João Paulo Kitajima,Rachel Adamson,Peter D. Ashton,Maria de Fatima Bonaldo,Patricia S. Coulson,Gary P. Dillon,Leonardo P. Farias,Sheila P. Gregório,Paulo L. Ho,Ricardo A. Leite,L. Cosme C. Malaquias,Regina C.P. Marques,Patricia A. Miyasato,Ana L. T. O. Nascimento,Fernanda Pires Ohlweiler,Eduardo M. Reis,Marcela A. Ribeiro,Renata G. Sá,Gaëlle C. Stukart,M. Bento Soares,Cybele Gargioni,Toshie Kawano,Vanderlei Rodrigues,Alda Maria Backx Noronha Madeira,R. Alan Wilson,Carlos Frederico Martins Menck,João C. Setubal,Luciana C. C. Leite,Emmanuel Dias-Neto +36 more
TL;DR: By analyzing automated Gene Ontology assignments, this work provides a detailed view of important S. mansoni biological systems, including characterization of metazoa-specific and eukarya-conserved genes, and identifies novel proteins to be investigated as vaccine candidates and potential drug targets.
Journal ArticleDOI
Comparative Genomics of Two Leptospira interrogans Serovars Reveals Novel Insights into Physiology and Pathogenesis
Ana L. T. O. Nascimento,Albert I. Ko,Albert I. Ko,Elizabeth A. L. Martins,Claudia Barros Monteiro-Vitorello,Paulo L. Ho,David A. Haake,David A. Haake,Sergio Verjovski-Almeida,Rudy A. Hartskeerl,Marilis V. Marques,Mariana Cabral de Oliveira,Carlos Frederico Martins Menck,Luciana C. C. Leite,Helaine Carrer,Luiz Lehmann Coutinho,Wim Degrave,Odir Antônio Dellagostin,Hamza El-Dorry,Emer S. Ferro,Maria Inês Tiraboschi Ferro,Luiz Roberto Furlan,Marcia Gamberini,E. A. Giglioti,Aristóteles Góes-Neto,Gustavo H. Goldman,Maria Helena S. Goldman,Ricardo Harakava,Selma M. B. Jeronimo,Inácio L.M. Junqueira-de-Azevedo,Edna Teruko Kimura,Eiko E. Kuramae,Eliana Gertrudes de Macedo Lemos,Manoel Victor Franco Lemos,Celso Luis Marino,Luiz R. Nunes,R. C. de Oliveira,Gonçalo A.G. Pereira,Marcelo S. Reis,A. Schriefer,Walter José Siqueira,P. Sommer,Siu Mui Tsai,Andrew J. G. Simpson,Jesus Aparecido Ferro,Luis Eduardo Aranha Camargo,João Paulo Kitajima,João C. Setubal,M. A. Van Sluys +48 more
TL;DR: Genome sequence analysis elucidates many of the novel aspects of leptospiral physiology relating to energy metabolism, oxygen tolerance, two-component signal transduction systems, and mechanisms of pathogenesis.
Journal ArticleDOI
Recombinant vaccines and the development of new vaccine strategies
TL;DR: Some of the major breakthroughs that have been achieved using recombinant vaccine technologies are discussed, as well as new approaches and strategies for vaccine development, including potential shortcomings and risks.
Journal ArticleDOI
Recombinant BCG Expressing LTAK63 Adjuvant induces Superior Protection against Mycobacterium tuberculosis.
Ivan P. Nascimento,Dunia Rodriguez,Carina Carvalho Dos Santos,Eduardo P. Amaral,Henrique K. Rofatto,Ana Paula Junqueira-Kipnis,E. D. C. Gonçalves,Maria Regina D'Império-Lima,Mario Hiroyuki Hirata,Célio Lopes Silva,Nathalie Winter,Brigitte Gicquel,Kingston H. G. Mills,Mariagrazia Pizza,Rino Rappuoli,Luciana C. C. Leite +15 more
TL;DR: It is suggested that BCG with low-level expression of the LTAK63 adjuvant induces a stronger immune response in the lungs conferring higher levels of protection, and a novel mechanism subsequently triggers a regulatory immune response, which then limits the pathology.