Luke Freeman-Mills

TL;DR: The clinical and demographic characteristics and COVID-19 outcomes in patients with cancer appear to be principally driven by age, gender, and comorbidities.

TL;DR: Both POLE mutation and MMR-D were associated with significantly reduced risk of recurrence compared with MMR-P colorectal cancers in multivariable analysis, which underscores the importance of rare biomarkers in precision cancer medicine, but raises important questions about how to identify and implement them in practice.

TL;DR: It is shown that cytoophidium formation occurs during nutrient deprivation in cultured cells, as well as in quiescent and starved neuroblasts of the Drosophila larval central nervous system, indicating that filament formation regulates pyrimidine synthesis in a normal developmental context.

TL;DR: The rapid emergence of COVID-19 has sent shockwaves through healthcare systems globally, with cancer patients at increased risk, and the interplay of the virus and host immune system has been implicated in the development of ARDS.