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M. George Cherian

Researcher at University of Western Ontario

Publications -  94
Citations -  6116

M. George Cherian is an academic researcher from University of Western Ontario. The author has contributed to research in topics: Metallothionein & Kidney. The author has an hindex of 37, co-authored 94 publications receiving 5899 citations. Previous affiliations of M. George Cherian include Umeå University & Örebro University.

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Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework

Edward J. Calabrese, +57 more
TL;DR: This article offers a set of recommendations that scientists believe can achieve greater conceptual harmony in dose-response terminology, as well as better understanding and communication across the broad spectrum of biological disciplines.
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Metallothioneins in human tumors and potential roles in carcinogenesis

TL;DR: The evidence supporting a role for MT in both intrinsic and acquired drug resistance is critically evaluated and it is difficult to conclude that MT is a more crucial factor than others.
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Metallothioneins and their role in the metabolism and toxicity of metals

TL;DR: The metallothioneins may also have an important role in regulating the normal absorption and homeostasis of zinc and copper as discussed by the authors, however, it is paradoxical, in that a protein synthesized within the cell to reduce toxicity, may, in itself, be toxic when excreted or leaked out from a cell to the extracellular space.
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Increased dietary cadmium absorption in mice and human subjects with iron deficiency

TL;DR: The intestinal adaptive response to iron deficiency in both experimental animals and human subjects leads to the increased absorption of cadmium, a potentially toxic element.
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Quantification of metallothioneins by a silver-saturation method

TL;DR: The binding of Ag+ to metallothionein (MT) was investigated, and a Ag-saturation assay was developed for the measurement of MT in tissues, and in cases where significant amounts of Cu-MT were present, the Cd-hem assay consistently underestimated the MT concentrations.