M
M. George Cherian
Researcher at University of Western Ontario
Publications - 94
Citations - 6116
M. George Cherian is an academic researcher from University of Western Ontario. The author has contributed to research in topics: Metallothionein & Kidney. The author has an hindex of 37, co-authored 94 publications receiving 5899 citations. Previous affiliations of M. George Cherian include Umeå University & Örebro University.
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Journal ArticleDOI
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework
Edward J. Calabrese,Kenneth Bachmann,A. John Bailer,P. Michael Bolger,Jonathan Borak,Lu Cai,Nina Cedergreen,M. George Cherian,Chuang Chin Chiueh,Thomas W. Clarkson,Ralph R. Cook,David M. Diamond,David J. Doolittle,Michael A. Dorato,Stephen O. Duke,Ludwig E. Feinendegen,Donald E. Gardner,Ronald W. Hart,Kenneth L. Hastings,A. Wallace Hayes,George R. Hoffmann,John A. Ives,Zbigniew Jaworowski,Thomas E. Johnson,Wayne B. Jonas,Norbert E. Kaminski,John G. Keller,James E. Klaunig,Thomas B. Knudsen,Walter J. Kozumbo,Teresa Lettieri,Shu Zheng Liu,Andre Maisseu,Kenneth I. Maynard,Edward J. Masoro,Roger O. McClellan,Harihara M. Mehendale,Carmel Mothersill,David B. Newlin,Herbert N. Nigg,Frederick W. Oehme,Robert F. Phalen,Martin A. Philbert,Suresh I. S. Rattan,Jim E. Riviere,Joseph Rodricks,Robert M. Sapolsky,Bobby R. Scott,Colin Seymour,David A. Sinclair,Joan Smith-Sonneborn,Elizabeth T. Snow,Linda P. Spear,Donald E. Stevenson,Yolene Thomas,Maurice Tubiana,Gary M. Williams,Mark P. Mattson +57 more
TL;DR: This article offers a set of recommendations that scientists believe can achieve greater conceptual harmony in dose-response terminology, as well as better understanding and communication across the broad spectrum of biological disciplines.
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Metallothioneins in human tumors and potential roles in carcinogenesis
TL;DR: The evidence supporting a role for MT in both intrinsic and acquired drug resistance is critically evaluated and it is difficult to conclude that MT is a more crucial factor than others.
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Metallothioneins and their role in the metabolism and toxicity of metals
TL;DR: The metallothioneins may also have an important role in regulating the normal absorption and homeostasis of zinc and copper as discussed by the authors, however, it is paradoxical, in that a protein synthesized within the cell to reduce toxicity, may, in itself, be toxic when excreted or leaked out from a cell to the extracellular space.
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Increased dietary cadmium absorption in mice and human subjects with iron deficiency
Peter R. Flanagan,Jenny S. McLellan,James V. Haist,M. George Cherian,M J Chamberlain,L. S. Valberg +5 more
TL;DR: The intestinal adaptive response to iron deficiency in both experimental animals and human subjects leads to the increased absorption of cadmium, a potentially toxic element.
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Quantification of metallothioneins by a silver-saturation method
TL;DR: The binding of Ag+ to metallothionein (MT) was investigated, and a Ag-saturation assay was developed for the measurement of MT in tissues, and in cases where significant amounts of Cu-MT were present, the Cd-hem assay consistently underestimated the MT concentrations.